ENSMUSG00000025503


Mus musculus

Features
Gene ID: ENSMUSG00000025503
  
Biological name :Taldo1
  
Synonyms : Q93092 / Taldo1 / Transaldolase
  
Possible biological names infered from orthology : P37837 / transaldolase 1
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 141392199
Gene end: 141402968
  
Corresponding Affymetrix probe sets: 10558903 (MoGene1.0st)   1425129_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000147332
Ensembl peptide - ENSMUSP00000026576
NCBI entrez gene - 21351     See in Manteia.
MGI - MGI:1274789
RefSeq - NM_011528
RefSeq Peptide - NP_035658
swissprot - A0A1B0GR11
swissprot - Q93092
Ensembl - ENSMUSG00000025503
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taldo1ENSDARG00000103369Danio rerio
 TALDO1ENSGALG00000037195Gallus gallus
 P37837ENSG00000177156Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001585  Transaldolase/Fructose-6-phosphate aldolase
 IPR004730  Transaldolase type 1
 IPR013785  Aldolase-type TIM barrel
 IPR018225  Transaldolase, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006002 fructose 6-phosphate metabolic process IEA
 biological_processGO:0006098 pentose-phosphate shunt IEA
 biological_processGO:0009052 pentose-phosphate shunt, non-oxidative branch IEA
 biological_processGO:0019682 glyceraldehyde-3-phosphate metabolic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0048029 monosaccharide binding IEA


Pathways (from Reactome)
Pathway description
Insulin effects increased synthesis of Xylulose-5-Phosphate
Pentose phosphate pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

 MP:0003806 abnormal nucleotide metabolism "impaired regulation of nucleotide levels in either production or breakdown of these structural components of nucleic acids" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

 MP:0004542 impaired acrosome reaction "abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Taldo1tm1Perl/Taldo1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

Allelic Composition: Taldo1tm1Perl/Taldo1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0009832 abnormal sperm mitochondrial sheath morphology "any structural anomaly or impairment of the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum" [PMID:14581499]
Show

Allelic Composition: Dnase2atm1Osa/Dnase2atm2Osa,Tg(Mx1-cre)1Cgn/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025503 Q93092 / Taldo1 / Transaldolase / P37837* / transaldolase 1*  / complex






 

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