ENSMUSG00000025626


Mus musculus

Features
Gene ID: ENSMUSG00000025626
  
Biological name :Phf6
  
Synonyms : PHD finger protein 6 / Phf6 / Q9D4J7
  
Possible biological names infered from orthology : Q8IWS0
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A5
Gene start: 52912266
Gene end: 52956943
  
Corresponding Affymetrix probe sets: 10599612 (MoGene1.0st)   1430415_at (Mouse Genome 430 2.0 Array)   1453761_at (Mouse Genome 430 2.0 Array)   1454625_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130358
Ensembl peptide - ENSMUSP00000077971
Ensembl peptide - ENSMUSP00000110497
NCBI entrez gene - 70998     See in Manteia.
MGI - MGI:1918248
RefSeq - NM_001290546
RefSeq - NM_027642
RefSeq Peptide - NP_001277475
RefSeq Peptide - NP_081918
swissprot - E9QAG2
swissprot - Q9D4J7
Ensembl - ENSMUSG00000025626
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phf6ENSDARG00000004046Danio rerio
 PHF6ENSGALG00000006094Gallus gallus
 PHF6ENSG00000156531Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phf11a / Q8BVM9 / PHD finger protein 11A / PHF11* / Q9UIL8* / PHD finger protein 11*ENSMUSG000000447036
Phf11c / PHF11* / Q9UIL8* / PHD finger protein 11*ENSMUSG000000911445
A6H5X4 / Phf11d / PHD finger protein 11 / PHF11* / Q9UIL8*ENSMUSG000000682455
Phf11b / PHF11* / Q9UIL8* / PHD finger protein 11*ENSMUSG000000916495
Gm6904 / PHF11* / Q9UIL8* / PHD finger protein 11*ENSMUSG000000908813


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR034732  Extended PHD (ePHD) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0015631 tubulin binding ISO
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0042393 histone binding ISO
 molecular_functionGO:0042826 histone deacetylase binding ISO
 molecular_functionGO:0043021 ribonucleoprotein complex binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051219 phosphoprotein binding ISO
 molecular_functionGO:0097110 scaffold protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Nphp1tm1.1(KOMP)Vlcg/Nphp1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Nphp1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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