ENSMUSG00000026192


Mus musculus

Features
Gene ID: ENSMUSG00000026192
  
Biological name :Atic
  
Synonyms : Atic / Bifunctional purine biosynthesis protein PURH Phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase / Q9CWJ9
  
Possible biological names infered from orthology : 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase / P31939
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: C3
Gene start: 71557150
Gene end: 71579631
  
Corresponding Affymetrix probe sets: 10347193 (MoGene1.0st)   1428506_at (Mouse Genome 430 2.0 Array)   1452811_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027384
NCBI entrez gene - 108147     See in Manteia.
MGI - MGI:1351352
RefSeq - NM_026195
RefSeq Peptide - NP_080471
swissprot - Q9CWJ9
Ensembl - ENSMUSG00000026192
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aticENSDARG00000016706Danio rerio
 ATICENSGALG00000003570Gallus gallus
 ATICENSG00000138363Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002695  Bifunctional purine biosynthesis protein PurH-like
 IPR011607  Methylglyoxal synthase-like domain
 IPR016193  Cytidine deaminase-like
 IPR024051  AICAR transformylase, duplicated domain superfamily
 IPR036914  Methylglyoxal synthase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003360 brainstem development IEA
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006189 "de novo" IMP biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0009259 ribonucleotide metabolic process IEA
 biological_processGO:0010035 response to inorganic substance IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0046452 dihydrofolate metabolic process IEA
 biological_processGO:0046654 tetrahydrofolate biosynthetic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003937 IMP cyclohydrolase activity IEA
 molecular_functionGO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026192 Atic / Q9CWJ9 / Bifunctional purine biosynthesis protein PURH Phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase / P31939* / 5-aminoimidazole-4-carboxamide ribonuc...  / complex






 

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