ENSMUSG00000026491


Mus musculus

Features
Gene ID: ENSMUSG00000026491
  
Biological name :Ahctf1
  
Synonyms : Ahctf1 / Protein ELYS / Q8CJF7
  
Possible biological names infered from orthology : AT-hook containing transcription factor 1 / Q8WYP5
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H4
Gene start: 179744894
Gene end: 179803680
  
Corresponding Affymetrix probe sets: 10360589 (MoGene1.0st)   1424712_at (Mouse Genome 430 2.0 Array)   1438816_at (Mouse Genome 430 2.0 Array)   1446472_at (Mouse Genome 430 2.0 Array)   1451459_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115795
Ensembl peptide - ENSMUSP00000027768
Ensembl peptide - ENSMUSP00000115253
Ensembl peptide - ENSMUSP00000119738
Ensembl peptide - ENSMUSP00000120551
NCBI entrez gene - 226747     See in Manteia.
MGI - MGI:1915033
RefSeq - XM_006496800
RefSeq - NM_026375
RefSeq Peptide - NP_080651
swissprot - F6XUM6
swissprot - F6S6E4
swissprot - F6QTR3
swissprot - Q8CJF7
swissprot - F6SJR1
Ensembl - ENSMUSG00000026491
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ahctf1ENSDARG00000077530Danio rerio
 AHCTF1ENSGALG00000010630Gallus gallus
 AHCTF1ENSG00000153207Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR025151  ELYS-like domain
 IPR032040  ELYS, beta-propeller domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030097 hemopoiesis TAS
 biological_processGO:0032465 regulation of cytokinesis IEA
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0051292 nuclear pore complex assembly IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore ISO
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005643 nuclear pore ISS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016363 nuclear matrix IDA
 cellular_componentGO:0031080 nuclear pore outer ring IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IMP
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002718 abnormal inner cell mass "malformed or absent cells of the blastocyst that develop into the body of the embryo" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Crebbptm1Pkb/Crebbptm1Pkb
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010380 inner cell mass apoptosis "the cells of the blastocyst that develop into the body of the embryo are undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Crebbptm1Pkb/Crebbptm1Pkb
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Crebbptm1Pkb/Crebbptm1Pkb
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0012114 absent inner cell mass proliferation 
Show

Allelic Composition: Crebbptm1Pkb/Crebbptm1Pkb
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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