MP:0000161 | scoliosis | "lateral and rotational curvature of the spine" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53770, J:66943] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0000186 | decreased circulating HDL cholesterol level | "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0000198 | hypophosphatemia | "abnormally low concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0000221 | decreased WBC count | "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0001146 | abnormal testis morphology | "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
Show
Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0001431 | abnormal eating behavior | "inability to consume or atypical consumption pattern" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:19212] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0001489 | decreased startle reflex | "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0001783 | decreased white fat amount | "reduced quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
Show
Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0002078 | abnormal glucose homeostasis | "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0002310 | resistance to fatty liver development | "less likely than the norm to to develop hepatic steatosis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0002644 | decreased circulating triglyceride level | "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0002727 | decreased circulating insulin level | "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0002966 | decreased circulating alkaline phosphatase level | "reduced activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0003179 | decreased platelet count | "fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0003383 | abnormal gluconeogenesis | "anomaly in the formation of glucose from noncarbohydrates, such as proteins or fat" [J:93896] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0004144 | hypotonia | "decreased muscle tension resulting in limpness of the muscles in the resting state, not to be confused with weakness" [hdene:Howard Dene , Mouse Genome Informatics Curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0004924 | abnormal behavior | "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0005036 | diarrhea | "abnormally frequent discharge of semi-solid or fluid fecal matter from the bowel" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gatmem1Btlr/Gatmem1Btlr Genetic Background: C57BL/6J-Gatmem1Btlr
Allelic Composition: Gatmm1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmm1Btlr
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MP:0005179 | decreased total circulating cholesterol level | "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0005292 | improved glucose tolerance | "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0005419 | hypoalbuminemia | "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0005560 | decreased circulating glucose level | "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0005567 | decreased circulating total protein level | "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0005659 | resistance to diet-induced obesity | "less likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0005668 | decreased circulating leptin level | "less than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0006086 | decreased body mass index | "less than normal average of a measure of weight for height " [ncbi:NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0008537 | increased susceptibility to induced colitis | "increased severity or induction threshold of colitis upon treatment of an organism with intestinal inflammation agents such as dextran sodium sulfate (DSS)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tap2m3Btlr/Tap2m3Btlr Genetic Background: C57BL/6J-Tap2m3Btlr
Allelic Composition: Gatmem1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmem1Btlr/Gatmm1Btlr
Allelic Composition: Gatmm1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmm1Btlr
Allelic Composition: Gatmm1Btlr/Gatm+ Genetic Background: C57BL/6J-Gatmm1Btlr
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MP:0008844 | decreased subcutaneous adipose tissue amount | "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0008873 | increased sensitivity to xenobiotics | "decrease in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tap2m3Btlr/Tap2m3Btlr Genetic Background: C57BL/6J-Tap2m3Btlr
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MP:0008883 | abnormal enterocyte proliferation | "anomaly in the ability of the enterocyte cell population to undergo expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tap2m3Btlr/Tap2m3Btlr Genetic Background: C57BL/6J-Tap2m3Btlr
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MP:0008885 | increased enterocyte apoptosis | "increase in the timing or the number of B cells undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tap2m3Btlr/Tap2m3Btlr Genetic Background: C57BL/6J-Tap2m3Btlr
Allelic Composition: Gatmm1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmm1Btlr
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MP:0008935 | decreased mean platelet volume | "reduced average content of platelet cells over normal" [MGI:mberry "Melissa Berry, Genetics Resources Curator"] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0009356 | decreased liver triglyceride level | "lower than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0009766 | increased sensitivity to xenobiotic induced morbidity/mortality | "decrease in the amount of a foreign compound required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gatmm1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmm1Btlr
Allelic Composition: Gatmm1Btlr/Gatm+ Genetic Background: C57BL/6J-Gatmm1Btlr
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MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0010053 | decreased grip strength | "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0010062 | decreased creatine concentration | "reduction in the amount per unit of an amino acid that is found in muscle tissue of vertebrates as phosphocreatine and supplies energy for muscle contraction when metabolized" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
Allelic Composition: Gatmem1Btlr/Gatmem1Btlr Genetic Background: C57BL/6J-Gatmem1Btlr
Allelic Composition: Gatmm1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmm1Btlr
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MP:0010068 | decreased red blood cell distribution width | "lower than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0010180 | increased susceptibility to weight loss | "greater decrease in body weight over time when compared to the average decrease in weight in response to dietary modification, fasting or caloric restriction" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gatmem1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmem1Btlr/Gatmm1Btlr
Allelic Composition: Gatmm1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmm1Btlr
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MP:0011468 | abnormal urine amino acid level | "any anomaly in the amount in the urine of a carboxylic acid containing one or more amino groups (-NH2) and a carboxyl (-COOH) group" [CHEBI:33709, MGI:csmith] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0011471 | decreased urine creatinine level | "a reduced amount of creatinine in the urine compared to the normal state" [MGI:csmith] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0011897 | decreased circulating unsaturated transferrin level | "reduction in the concentration of transferrin that is not saturated (bound) with iron; this represents the reserve capacity of transferrin and is often measured by the Unsaturated Iron Binding Capacity (UIBC) test" [MGI:csmith] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0011940 | decreased food intake | "reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith] |
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Allelic Composition: Gatmtm1b(KOMP)Wtsi/Gatmtm1b(KOMP)Wtsi Genetic Background: C57BL/6N-Gatmtm1b(KOMP)Wtsi/Ieg
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MP:0013482 | abnormal duodenum crypts of Lieberkuhn morphology | "any structural anomaly of the intestinal crypts located in the mucosa of the duodenum, the first division of the small intestine that extends from the pyloris to the junction with the jejunum" [MGI:Anna] |
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Allelic Composition: Gatmm1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmm1Btlr
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MP:0013956 | decreased colon length | "reduced length of the portion of the large intestine between the cecum and the rectum" [ISBN:0683400088] |
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Allelic Composition: Gatmem1Btlr/Gatmem1Btlr Genetic Background: C57BL/6J-Gatmem1Btlr
Allelic Composition: Gatmem1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmem1Btlr/Gatmm1Btlr
Allelic Composition: Gatmm1Btlr/Gatmm1Btlr Genetic Background: C57BL/6J-Gatmm1Btlr
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MP:0030016 | increased adipocyte glucose uptake | "increased ability of adipocytes to take in glucose" [MGI:anna] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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MP:0030021 | increased muscle cell glucose uptake | "increased ability of muscle cells to take in glucose" [MGI:anna] |
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Allelic Composition: Trpv5m1Btlr/Trpv5m1Btlr Genetic Background: C57BL/6J-Trpv5m1Btlr
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