ENSMUSG00000027317


Mus musculus

Features
Gene ID: ENSMUSG00000027317
  
Biological name :Ppp1r14d
  
Synonyms : Ppp1r14d / Protein phosphatase 1 regulatory subunit 14D / Q7TT52
  
Possible biological names infered from orthology : protein phosphatase 1 regulatory inhibitor subunit 14D / Q9NXH3
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E5
Gene start: 119218119
Gene end: 119229906
  
Corresponding Affymetrix probe sets: 10486191 (MoGene1.0st)   1417990_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000075453
Ensembl peptide - ENSMUSP00000106444
NCBI entrez gene - 72112     See in Manteia.
MGI - MGI:1919362
RefSeq - NM_001290796
RefSeq - NM_028104
RefSeq Peptide - NP_001277725
RefSeq Peptide - NP_082380
swissprot - Q7TT52
Ensembl - ENSMUSG00000027317
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:162989ENSDARG00000110496Danio rerio
 ENSGALG00000024469Gallus gallus
 Q9NXH3ENSG00000166143Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q62084 / Ppp1r14b / Protein phosphatase 1 regulatory subunit 14B / Q96C90* / protein phosphatase 1 regulatory inhibitor subunit 14B*ENSMUSG0000005661216
Q91VC7 / Ppp1r14a / Protein phosphatase 1 regulatory subunit 14A / Q96A00* / protein phosphatase 1 regulatory inhibitor subunit 14A*ENSMUSG0000003716615
Q8R4S0 / Ppp1r14c / protein phosphatase 1, regulatory (inhibitor) subunit 14c / Q8TAE6*ENSMUSG0000004065314
4933415F23Rik / RIKEN cDNA 4933415F23 geneENSMUSG0000007373014


Protein motifs (from Interpro)
Interpro ID Name
 IPR008025  CPI-17
 IPR036658  CPI-17 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0042325 regulation of phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002753 dilated left ventricle "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0003921 abnormal left ventricle morphology "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0005140 decreased cardiac muscle contractility "inability or reduced ability of the heart muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0005599 increased cardiac muscle contractility "greater than the normal ability of the heart muscle to shorten or to develop increased tension " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr