ENSMUSG00000027411


Mus musculus

Features
Gene ID: ENSMUSG00000027411
  
Biological name :Vps16
  
Synonyms : Vps16 / VSP16 CORVET/HOPS core subunit
  
Possible biological names infered from orthology : Q9H269 / VPS16, CORVET/HOPS core subunit
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F1
Gene start: 130424339
Gene end: 130444269
  
Corresponding Affymetrix probe sets: 10476136 (MoGene1.0st)   1416254_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115899
Ensembl peptide - ENSMUSP00000028900
NCBI entrez gene - 80743     See in Manteia.
MGI - MGI:2136772
RefSeq - XM_006500430
RefSeq - XM_017319344
RefSeq - NM_030559
RefSeq - XM_017319343
RefSeq Peptide - NP_085036
swissprot - G3X8X7
swissprot - A2BI90
Ensembl - ENSMUSG00000027411
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps16ENSDARG00000059902Danio rerio
 VPS16ENSG00000215305Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006925  Vps16, C-terminal
 IPR006926  Vps16, N-terminal
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016534  Vacuolar protein sorting-associated protein 16


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007033 vacuole organization IEA
 biological_processGO:0008333 endosome to lysosome transport IEA
 biological_processGO:0097352 autophagosome maturation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030897 HOPS complex IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cxcr4tm2Yzo/Cxcr4tm2Yzo,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005323 dystonia "impairment of muscle tone resulting in prolonged muscle contraction and involuntary movements such as repetitive movements, or twisting or writhing of the limbs" [J:84533]
Show

Allelic Composition: Cxcr4tm2Yzo/Cxcr4tm2Yzo,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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