Manteia

ENSMUSG00000027427

Mus musculus

Features

Gene ID:	ENSMUSG00000027427

Biological name :	Polr3f

Synonyms :	Polr3f / polymerase (RNA) III (DNA directed) polypeptide F / Q921X6

Possible biological names infered from orthology :	Q9H1D9 / RNA polymerase III subunit F

Species:	Mus musculus

Chr. number:	2
Strand:	1
Band:	G1
Gene start:	144527718
Gene end:	144541995

Corresponding Affymetrix probe sets:	10476691 (MoGene1.0st) 1429686_at (Mouse Genome 430 2.0 Array) 1430328_at (Mouse Genome 430 2.0 Array) 1431999_at (Mouse Genome 430 2.0 Array) 1439075_at (Mouse Genome 430 2.0 Array) 1451773_s_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000028914 Ensembl peptide - ENSMUSP00000105644 NCBI entrez gene - 70408 See in Manteia. MGI - MGI:1924086 RefSeq - NM_029763 RefSeq Peptide - NP_084039 swissprot - Q921X6 swissprot - Q9CZ23 Ensembl - ENSMUSG00000027427

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR007832	RNA polymerase Rpc34
IPR016049	RNA polymerase Rpc34-like
IPR036388	Winged helix-like DNA-binding domain superfamily
IPR036390	Winged helix DNA-binding domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0002376	immune system process	IEA
biological_process	GO:0006383	transcription by RNA polymerase III	IEA
biological_process	GO:0032728	positive regulation of interferon-beta production	IEA
biological_process	GO:0045087	innate immune response	IEA
biological_process	GO:0045089	positive regulation of innate immune response	IEA
biological_process	GO:0051607	defense response to virus	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005666	DNA-directed RNA polymerase III complex	IEA
molecular_function	GO:0001056	RNA polymerase III activity	IBA
molecular_function	GO:0003690	double-stranded DNA binding	IEA
molecular_function	GO:0003899	DNA-directed 5"-3" RNA polymerase activity	IEA

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002073	abnormal hair growth	"absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Xbp1^{tm1a(EUCOMM)Wtsi}/Xbp1⁺ Genetic Background: C57BL/6N-Xbp1^{tm1a(EUCOMM)Wtsi}/Ics
MP:0005017	decreased B cell number	"fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Xbp1^{tm1a(EUCOMM)Wtsi}/Xbp1⁺ Genetic Background: C57BL/6N-Xbp1^{tm1a(EUCOMM)Wtsi}/Ics
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Pitx3^{tm1.1(KOMP)Vlcg}/Pitx3^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Pitx3^{tm1.1(KOMP)Vlcg}/J

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000028099	Polr3c / Q9D483 / polymerase (RNA) III (DNA directed) polypeptide C / Q9BUI4* / RNA polymerase III subunit C*	/ complex
ENSMUSG00000028104	Q8R0C0 / Polr3gl / DNA-directed RNA polymerase III subunit RPC7-like / Q9BT43* / AC243547.3* / RNA polymerase III subunit G like*	/ complex
ENSMUSG00000035834	Polr3g / Q6NXY9 / DNA-directed RNA polymerase III subunit RPC7 / O15318* / RNA polymerase III subunit G*	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr