ENSMUSG00000027661


Mus musculus

Features
Gene ID: ENSMUSG00000027661
  
Biological name :Slc2a10
  
Synonyms : Q8VHD6 / Slc2a10 / solute carrier family 2 (facilitated glucose transporter), member 10
  
Possible biological names infered from orthology : O95528 / solute carrier family 2 member 10
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H3
Gene start: 165503787
Gene end: 165519917
  
Corresponding Affymetrix probe sets: 10478692 (MoGene1.0st)   1419434_at (Mouse Genome 430 2.0 Array)   1449477_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029196
NCBI entrez gene - 170441     See in Manteia.
MGI - MGI:2156687
RefSeq - NM_130451
RefSeq Peptide - NP_569718
swissprot - A2A4V1
swissprot - Q8VHD6
Ensembl - ENSMUSG00000027661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc2a10ENSDARG00000090820Danio rerio
 SLC2A10ENSGALG00000004498Gallus gallus
 O95528ENSG00000197496Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BFW9 / Slc2a12 / solute carrier family 2 (facilitated glucose transporter), member 12 / Q8TD20* / solute carrier family 2 member 12*ENSMUSG0000003749039
Q3UHK1 / Slc2a13 / solute carrier family 2 (facilitated glucose transporter), member 13 / Q96QE2* / solute carrier family 2 member 13*ENSMUSG0000003629830
Q9JIF3 / Slc2a8 / solute carrier family 2, (facilitated glucose transporter), member 8 / Q9NY64* / solute carrier family 2 member 8*ENSMUSG0000002679125
Slc2a6 / solute carrier family 2 (facilitated glucose transporter), member 6 / Q9UGQ3* / solute carrier family 2 member 6*ENSMUSG0000003606724


Protein motifs (from Interpro)
Interpro ID Name
 IPR003663  Sugar/inositol transporter
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008643 carbohydrate transport IEA
 biological_processGO:0046323 glucose import IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1902600 proton transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005351 carbohydrate:proton symporter activity IBA
 molecular_functionGO:0005355 glucose transmembrane transporter activity IBA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Cellular hexose transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
Show

Allelic Composition: Foxa1tm1Gsc/Foxa1+
Genetic Background: involves: 129P2/OlaHsd

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxa1tm1Gsc/Foxa1+
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0002191 abnormal artery morphology "malformation of the blood vessels that carry blood away from the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0002964 aortic elastic tissue lesions "focal pathological changes in the elastic lamella of the muscular layer of the main trunk of the arterial system" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0003209 abnormal pulmonary elastic fiber morphology "malformation of a slender connective tissue fiber in pulmonary tissue characterized by great elasticity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0003211 abnormal aorta elastic fiber morphology "malformation of a slender connective tissue fiber in aortic tissue characterized by great elasticity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0004007 abnormal lung vasculature "malformation or disorganization of the blood vessels of the lung" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0006083 abnormal vascular elastic tissue "malformation in the tissue that is found in the tunica media of the vessels wall and allows vessels to stretch" [smb:Susan M Bello, Mouse Genome Informatics Curator, ncbi:NCBI request]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0009866 abnormal aorta wall morphology "any structural anomaly of the part of the aorta that encloses the luminal space" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0009869 abnormal descending aorta morphology "any strucutral anomaly of the part of the aorta extending from the arch of aorta to the point where it divides into the common iliac arteries" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0010903 abnormal pulmonary alveolus wall morphology 
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

 MP:0011309 abnormal kidney arterial blood vessel morphology "any structural anomaly of the network of tubes that supply blood to the renal tissues" [MGI:csmith]
Show

Allelic Composition: Slc2a10G128E/Slc2a10G128E
Genetic Background: C3HeB/FeJ-Slc2a10G128E

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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