MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Pax6Aey80/Pax6+ Genetic Background: C3HeB/FeJ-Pax6Aey80
Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0000119 | abnormal tooth eruption | "anomalies in the passage of a tooth through the alveolar process and perforation of the gums" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fgf9tm1.2Fwan/Fgf9tm1.2Fwan Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
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MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
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MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
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MP:0000285 | abnormal cardiac valve morphology | "malformation of the membranous folds of the heart that prevent reflux of fluid" [J:18048] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
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MP:0000343 | altered response to myocardial infarction | "change in the physiological response to necrosis of the cardiac tissue, often resulting from the sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Postntm1Jmol/Postntm1Jmol Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Postntm1Kudo/Postntm1Kudo Genetic Background: B6.Cg-Postntm1Kudo
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MP:0000458 | abnormal mandible morphology | "malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Pax6Aey80/Pax6+ Genetic Background: C3HeB/FeJ-Pax6Aey80
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MP:0001127 | small ovary | "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
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MP:0001258 | decreased body length | "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+ Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
Allelic Composition: Postntm1Jmol/Postntm1Jmol Genetic Background: involves: 129/Sv * C57BL/6
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
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MP:0001523 | impaired righting response | "reduced ability or greater amount of time needed to recover from supine position" [J:25565] |
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Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+ Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H
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MP:0001544 | abnormal cardiovascular system physiology | "anomalous function of the blood, blood vessels, and/or the heart" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Myh6tm3.1Jse/Myh6+ Genetic Background: involves: 129X1/SvJ
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
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MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Kat6atm1Avo/Kat6a+ Genetic Background: involves: 129 * BALB/c * FVB/N
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MP:0002188 | small heart | "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044] |
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Allelic Composition: Postntm1Jmol/Postntm1Jmol Genetic Background: involves: 129/Sv * C57BL/6
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MP:0002576 | abnormal enamel morphology | "malformation of the hard outer coating of the exposed portion of the tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Fgf9tm1.2Fwan/Fgf9tm1.2Fwan Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: B6.Cg-Postntm1Sjc
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MP:0002637 | small uterus | "reduced size of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0002650 | abnormal ameloblast morphology | "malformation of the epithelial cells of the inner layer of the enamel organ of the developing tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Fgf9tm1.2Fwan/Fgf9tm1.2Fwan Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0002764 | short tibia | " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0002818 | abnormal dentin morphology | "defects in the hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Fgf9tm1.2Fwan/Fgf9tm1.2Fwan Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0002834 | decreased heart weight | "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0002968 | increased circulating alkaline phosphatase level | "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0003109 | short femur | "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0003141 | cardiac fibrosis | "formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Myh6tm1Jse/Myh6+,Postntm1Jmol/Postntm1Jmol Genetic Background: involves: 129S/SvEv * 129X1/SvJ
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MP:0003566 | abnormal cell adhesion | "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Postntm1Jmol/Postntm1Jmol Genetic Background: involves: 129/Sv * C57BL/6
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MP:0003668 | abnormal periodontal ligament morphology | "any structural anomaly in the fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone; normally extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:66512] |
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Allelic Composition: Fgf9tm1.2Fwan/Fgf9tm1.2Fwan Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: B6.Cg-Postntm1Sjc
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MP:0003699 | abnormal female reproductive system physiology | "anomaly in the function of the female organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0003721 | increased tumor growth/size | "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Postntm1Kudo/Postntm1Kudo Genetic Background: B6.Cg-Postntm1Kudo
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MP:0003723 | abnormal long bone morphology | "malformation of any of the several elongated bones of the extremities
" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0003795 | abnormal bone structure | |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0003930 | abnormal tooth hard tissue morphology | "defects in the hard portion of the tooth surrounding the pulp, including the dentin, enamel and the cementum on the root" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Fgf9tm1.2Fwan/Fgf9tm1.2Fwan Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0003961 | decreased lean body mass | "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator] |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0004189 | abnormal alveolar process | "any structural anomaly of the thickened ridge of bone in the mandible and maxilla that holds the tooth sockets" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: B6.Cg-Postntm1Sjc
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MP:0004343 | small scapula | "reduced size of either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0004351 | short humerus | "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0004355 | short radius | "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0004672 | short ribs | "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0004674 | thin ribs | "a more slender appearance of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0004984 | increased osteoclast cell number | "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: B6.Cg-Postntm1Sjc
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MP:0005166 | decreased susceptiblity to injury | "less than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Postntm1Jmol/Postntm1Jmol Genetic Background: involves: 129/Sv * C57BL/6
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MP:0005352 | small skull | "less than the normal size of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0005358 | abnormal incisor morphology | "structural defect of the long pointed teeth; most anterior and prominent in the jaw" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85574] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0005627 | increased circulating potassium level | "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission] |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0006395 | abnormal epiphyseal plate morphology | "any structural anomaly of the cartilaginous center of ossification on the bones permitting growth of the bone in both directions during development" [MESH:A02.835.232.251.352] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: B6.Cg-Postntm1Sjc
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MP:0008874 | decreased sensitivity to xenobiotics | "increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Myh6tm1Jse/Myh6+,Postntm1Jmol/Postntm1Jmol Genetic Background: involves: 129S/SvEv * 129X1/SvJ
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MP:0009009 | absent estrous cycle | "failure of female animals to enter or progress through their sexual cycle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0009070 | small oviduct | "reduced size of the tube through which the ova pass from the ovary to the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0009763 | increased sensitivity to induced morbidity/mortality | "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1Kudo/Postntm1Kudo Genetic Background: B6.Cg-Postntm1Kudo
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MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0010124 | decreased bone mineral content | "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0010879 | decreased trabecular bone volume | "decrease in the amount of space occupied by trabecular bone tissue in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: B6.Cg-Postntm1Sjc
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MP:0010965 | decreased compact bone volume | |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: B6.Cg-Postntm1Sjc
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0011275 | abnormal behavioral response to light | "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2] |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0011396 | abnormal sleep behavior | "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb] |
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Allelic Composition: Postntm1.1(KOMP)Vlcg/Postntm1.1(KOMP)Vlcg Genetic Background: C57BL/6N-Postntm1.1(KOMP)Vlcg/J
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MP:0030132 | periodontium inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the periodontium (including the gums and supporting structures of the teeth)" [MGI:anna] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0030451 | abnormal dentin mineralization | "anomaly in the process by which calcium salts are deposited into dentin" [GO:0097188] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0030494 | abnormal molar root morphology | "any structural anomaly of the part of a molar tooth that is implanted in the gum" [MGI:anna] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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MP:0030524 | abnormal tooth root resorption | "pathologic resorption in which cementum or dentin is lost from the root of a tooth owing to cementoclastic or osteoclastic activity in conditions such as trauma of occlusion or neoplasms" [MESH:D012391] |
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Allelic Composition: Postntm1Sjc/Postntm1Sjc Genetic Background: involves: C57BL/6
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