ENSMUSG00000027835


Mus musculus

Features
Gene ID: ENSMUSG00000027835
  
Biological name :Pdcd10
  
Synonyms : Pdcd10 / Programmed cell death protein 10 / Q8VE70
  
Possible biological names infered from orthology : programmed cell death 10 / Q9BUL8
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: E3
Gene start: 75516490
Gene end: 75556856
  
Corresponding Affymetrix probe sets: 10489041 (MoGene1.0st)   10498771 (MoGene1.0st)   1448527_at (Mouse Genome 430 2.0 Array)   1448528_at (Mouse Genome 430 2.0 Array)   1458938_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124421
Ensembl peptide - ENSMUSP00000125752
Ensembl peptide - ENSMUSP00000029424
NCBI entrez gene - 56426     See in Manteia.
MGI - MGI:1928396
RefSeq - NM_019745
RefSeq Peptide - NP_062719
swissprot - Q8VE70
swissprot - E0CY82
swissprot - F8WI55
Ensembl - ENSMUSG00000027835
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CT027583.1ENSDARG00000111952Danio rerio
 PDCD10ENSGALG00000009477Gallus gallus
 PDCD10ENSG00000114209Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009652  Programmed cell death protein 10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0044319 wound healing, spreading of cells IEA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051683 establishment of Golgi localization IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 biological_processGO:0090051 negative regulation of cell migration involved in sprouting angiogenesis IEA
 biological_processGO:0090168 Golgi reassembly IEA
 biological_processGO:0090316 positive regulation of intracellular protein transport IEA
 biological_processGO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000260 abnormal angiogenesis "aberrant process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000291 enlarged pericardium "extended fibroserous membrane covering the heart and beginning of the great vessels" [J:29971]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0000433 microcephaly "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0001394 circling "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0001606 impaired hematopoiesis "atypical process of blood cell formation with the result of fewer of these cells being formed" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0001622 abnormal vasculogenesis "aberrant process of the initial establishment of the vascular network " [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Cnr1tm1Map/Cnr1tm1Map,Tg(HD82Gln)81Gschi/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * CD-1

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Kwhi/Pdcd10tm1Kwhi,Tg(Tek-cre)1Ywa/?
Genetic Background: involves: C57BL/6 * SJL

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Kwhi/Pdcd10tm1Kwhi,Tg(Tek-cre)1Ywa/?
Genetic Background: involves: C57BL/6 * SJL

 MP:0002182 abnormal astrocyte morphology "anomalous structure, number or compostion of one of the large neuroglia cells of nervous tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Kwhi/Pdcd10tm1Kwhi,Tg(Tek-cre)1Ywa/?
Genetic Background: involves: C57BL/6 * SJL

 MP:0002463 abnormal neutrophil physiology "abnormal function of these granular leukocytes, which stain with neutral dyes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Lyz2tm1(cre)Ifo/Lyz2+,Pdcd10tm1Wami/Pdcd10tm1Wami
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0002652 thin myocardial wall "thinly developed cardiac muscle layers" [il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0002792 abnormal retinal vascularization "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ccm2tm1.1Etl/Ccm2tm1Etl,Tg(Cdh5-cre/ERT2)1Rha/0
Genetic Background: involves: 129 * C57BL/6

 MP:0002947 hemangioma "proliferation of blood vessels leading to a mass that resembles a neoplasm" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:87544]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

 MP:0003227 abnormal vascular branching morphogenesis "increase, decrease or anomaly in the process by which new vessels sprout off pre-existing vessels" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0003229 abnormal vitelline vasculature "malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0003354 astrocytosis "a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

 MP:0003544 abnormal vascular endothelial cell migration "anomaly in the movement of endothelial cell or their precursors to the appropriate location in the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95387]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0003717 pallor "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0003719 abnormal pericyte morphology "malformation in the connective tissue cells that occurs around capillaries or other small blood vessels " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Kwhi/Pdcd10tm1Kwhi,Tg(Tek-cre)1Ywa/?
Genetic Background: involves: C57BL/6 * SJL

 MP:0003974 abnormal endocardium morphology "malformation of the thin serous membrane, primarily composed of endothelial tissue, that lines the interior of the heart" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0004068 dilated dorsal aorta "an expansion in the volume of the dorsal region of the main trunk of the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0004076 abnormal vitelline vascular remodelling "anomaly in the conversion of the primary (honeycomb-like) vascular plexus of the yolk sac into a mature vascular network" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0004154 renal tubular necrosis "pathological cell death in the proximal and/or distal renal tubules, usually due to irreversible damage " [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Lyz2tm1(cre)Ifo/Lyz2+,Pdcd10tm1Wami/Pdcd10tm1Wami
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0004783 abnormal cardinal vein morphology "any structural anomaly of any of the four veins in the developing vertebrate embryo which run along each side of the vertebral column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

Allelic Composition: Pdcd10tm1Kwhi/Pdcd10tm1Kwhi,Tg(Tek-cre)1Ywa/?
Genetic Background: involves: C57BL/6 * SJL

 MP:0004787 abnormal dorsal aorta morphology "any structural anomaly of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation" [ISBN:0-914294-08-3 "Gray s Anatomy"]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0004938 dilated vasculature "stretched or widened aperture of the luminal space of the network of tubes that carries blood through the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0004950 abnormal brain vasculature "any structural anomaly of the blood vessel network of the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

Allelic Composition: Pdcd10tm1Kwhi/Pdcd10tm1.1Kwhi,Tg(Pdgfb-icre/ERT2)1Frut/?
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Pdcd10tm1Arte/Pdcd10tm1Arte,Tg(Cdh5-cre/ERT2)1Rha/0
Genetic Background: involves: C57BL/6

 MP:0005065 abnormal neutrophil morphology "structural anomaly of the granular leukocytes that have a three- to five-lobed nucleus and a cytoplasm that contains inconspicuous granules stainable by neutral dyes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Lyz2tm1(cre)Ifo/Lyz2+,Pdcd10tm1Wami/Pdcd10tm1Wami
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0005238 increased brain size "larger than the normal physical proportions of the brain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:57958]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

 MP:0005329 abnormal cardiac muscle morphology "anomalous structure of the involuntary muscle comprising the myocardium " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0005553 increased circulating creatinine level "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Lyz2tm1(cre)Ifo/Lyz2+,Pdcd10tm1Wami/Pdcd10tm1Wami
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6

 MP:0006082 CNS inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the brain and/or spinal cord" [smb:Susan M Bello, Mouse Genome Informatics Curator, ncbi:NCBI request]
Show

Allelic Composition: Pdcd10tm1Kwhi/Pdcd10tm1Kwhi,Tg(Tek-cre)1Ywa/?
Genetic Background: involves: C57BL/6 * SJL

 MP:0009577 abnormal developmental vascular remodeling "any anomaly in the process by which existing vessels are reorganized during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0010503 myocardial trabeculae hypoplasia "underdevelopment or reduced size of the supporting bundles of muscular fibers lining the walls of the heart, usually due to a reduced number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Cnr1tm1Map/Cnr1tm1Map,Tg(HD82Gln)81Gschi/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * CD-1

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

Allelic Composition: Pdcd10tm1Kwhi/Pdcd10tm1Kwhi,Tg(Tek-cre)1Ywa/?
Genetic Background: involves: C57BL/6 * SJL

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0011107 partial embryonic lethality before turning of embryo "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Ncoa3tm1Jxu/Ncoa3tm1Jxu
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0012253 abnormal intersomitic vessel morphology "any structural anomaly of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites" [MGI:anna]
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Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0012676 dilated brain ventricles "the luminal space of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord is increased in volume or area, usually with an increase in contained fluid" [MGI:anna]
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Allelic Composition: Pdcd10tm1Wami/Pdcd10tm1Wami,Tg(GFAP-cre)25Mes/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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