ENSMUSG00000027875


Mus musculus

Features
Gene ID: ENSMUSG00000027875
  
Biological name :Hmgcs2
  
Synonyms : Hmgcs2 / Hydroxymethylglutaryl-CoA synthase, mitochondrial / P54869
  
Possible biological names infered from orthology : 3-hydroxy-3-methylglutaryl-CoA synthase 2 / P54868
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.2
Gene start: 98280435
Gene end: 98310738
  
Corresponding Affymetrix probe sets: 10494643 (MoGene1.0st)   1423858_a_at (Mouse Genome 430 2.0 Array)   1431833_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000088249
Ensembl peptide - ENSMUSP00000113296
NCBI entrez gene - 15360     See in Manteia.
MGI - MGI:101939
RefSeq - NM_008256
RefSeq Peptide - NP_032282
swissprot - P54869
Ensembl - ENSMUSG00000027875
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HMGCS2ENSGALG00000002960Gallus gallus
 HMGCS2ENSG00000134240Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hmgcs1 / Q8JZK9 / Hydroxymethylglutaryl-CoA synthase, cytoplasmic / Q01581* / 3-hydroxy-3-methylglutaryl-CoA synthase 1*ENSMUSG0000009393060


Protein motifs (from Interpro)
Interpro ID Name
 IPR000590  Hydroxymethylglutaryl-coenzyme A synthase, active site
 IPR010122  Hydroxymethylglutaryl-CoA synthase, eukaryotic
 IPR013528  Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
 IPR013746  Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain
 IPR016039  Thiolase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0006695 cholesterol biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008202 steroid metabolic process IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0008299 isoprenoid biosynthetic process IEA
 biological_processGO:0016126 sterol biosynthetic process IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004421 hydroxymethylglutaryl-CoA synthase activity IDA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of Ketone Bodies


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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