ENSMUSG00000027963


Mus musculus

Features
Gene ID: ENSMUSG00000027963
  
Biological name :Extl2
  
Synonyms : Exostosin-like 2 / Extl2 / Q9ES89
  
Possible biological names infered from orthology : exostosin like glycosyltransferase 2 / Q9UBQ6
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: G1
Gene start: 116007462
Gene end: 116029017
  
Corresponding Affymetrix probe sets: 10495539 (MoGene1.0st)   1422538_at (Mouse Genome 430 2.0 Array)   1422539_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029575
Ensembl peptide - ENSMUSP00000102110
Ensembl peptide - ENSMUSP00000102111
NCBI entrez gene - 58193     See in Manteia.
MGI - MGI:1889574
RefSeq - XM_017319674
RefSeq - NM_001163514
RefSeq - NM_001163515
RefSeq - NM_021388
RefSeq - XM_006501827
RefSeq - XM_011240177
RefSeq Peptide - NP_001156986
RefSeq Peptide - NP_001156987
RefSeq Peptide - NP_067363
swissprot - Q3TSR0
swissprot - Q9ES89
Ensembl - ENSMUSG00000027963
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 extl2ENSDARG00000063191Danio rerio
 EXTL2ENSGALG00000027984Gallus gallus
 EXTL2ENSG00000162694Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Extl3 / exostosin like glycosyltransferase 3 / O43909*ENSMUSG0000002197829
Ext2 / P70428 / Mus musculus exostoses (multiple) 2 (Ext2), transcript variant 1, mRNA. / Q93063* / exostosin glycosyltransferase 2*ENSMUSG0000002719828
Ext1 / P97464 / Exostosin-1 / Q16394* / exostosin glycosyltransferase 1*ENSMUSG0000006173128
Extl1 / Q9JKV7 / Exostosin-like 1 / Q92935* / exostosin like glycosyltransferase 1*ENSMUSG0000002883824


Protein motifs (from Interpro)
Interpro ID Name
 IPR015338  Exostosin , C-terminal
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006044 N-acetylglucosamine metabolic process IMP
 biological_processGO:0019276 UDP-N-acetylgalactosamine metabolic process IMP
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity ISO
 molecular_functionGO:0005539 glycosaminoglycan binding IMP
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030145 manganese ion binding IMP
 molecular_functionGO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity IMP
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ilktm2Star/Ilk+,Itgb3tm1Hyn/Itgb3+
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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