ENSMUSG00000028102


Mus musculus

Features
Gene ID: ENSMUSG00000028102
  
Biological name :Pex11b
  
Synonyms : Peroxisomal membrane protein 11B / Pex11b / Q9Z210
  
Possible biological names infered from orthology : O96011 / peroxisomal biogenesis factor 11 beta
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.1
Gene start: 96635376
Gene end: 96645366
  
Corresponding Affymetrix probe sets: 10494460 (MoGene1.0st)   1420460_a_at (Mouse Genome 430 2.0 Array)   1451213_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115956
Ensembl peptide - ENSMUSP00000126631
Ensembl peptide - ENSMUSP00000037962
Ensembl peptide - ENSMUSP00000113365
NCBI entrez gene - 18632     See in Manteia.
MGI - MGI:1338882
RefSeq - NM_001162387
RefSeq - NM_001162388
RefSeq - NM_011069
RefSeq Peptide - NP_001155860
RefSeq Peptide - NP_035199
RefSeq Peptide - NP_001155859
swissprot - Q9Z210
swissprot - D6RFR1
swissprot - E9PXK7
Ensembl - ENSMUSG00000028102
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pex11bENSDARG00000069147Danio rerio
 O96011ENSG00000131779Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm42957 / O96011* / PEX11B* / peroxisomal biogenesis factor 11 beta*ENSMUSG0000010644785
Pex11a / Q9Z211 / Peroxisomal membrane protein 11A / O75192* / peroxisomal biogenesis factor 11 alpha*ENSMUSG0000003054537


Protein motifs (from Interpro)
Interpro ID Name
 IPR008733  Peroxisomal biogenesis factor 11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007031 peroxisome organization ISO
 biological_processGO:0007165 signal transduction ISS
 biological_processGO:0016559 peroxisome fission IEA
 biological_processGO:0044375 regulation of peroxisome size IBA
 biological_processGO:0051260 protein homooligomerization ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005777 peroxisome ISO
 cellular_componentGO:0005778 peroxisomal membrane ISO
 cellular_componentGO:0005779 integral component of peroxisomal membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0042803 protein homodimerization activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000074 abnormal neurocranium morphology "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
Show

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Chrna5tm1Mdb/Chrna5tm1Mdb,Chrnb4tm1Mdb/Chrnb4tm1Mdb
Genetic Background: B6.129-Chrnb4tm1Mdb Chrna5tm1Mdb

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000597 delayed hepatic development "late onset of the induction and/or differentiation of the liver" [J:18048]
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Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000849 abnormal cerebellum morphology "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Grin2btm1.1Jlbr/Grin2btm1.1Jlbr,Neurod6tm1(cre)Kan/Neurod6+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: B6.129-Pex11btm1Sjg

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
Show

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pex11atm1Sjg/Pex11atm1Sjg,Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002081 perinatal lethality "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pex11atm1Sjg/Pex11atm1Sjg,Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002088 abnormal embryonic growth/weight/body size "limited or accelerated growth or development apparent before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pex11atm1Sjg/Pex11atm1Sjg,Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003203 increased neuron apoptosis "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Grin2btm1.1Jlbr/Grin2btm1.1Jlbr,Neurod6tm1(cre)Kan/Neurod6+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: B6.129-Pex11btm1Sjg

 MP:0003674 oxidative stress "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Grin2btm1.1Jlbr/Grin2btm1.1Jlbr,Neurod6tm1(cre)Kan/Neurod6+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: B6.129-Pex11btm1Sjg

 MP:0005439 decreased glycogen level "less than the normal concentration of this readily converted carbohydrate reserve, found in most tissues of the body, especially liver and muscle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pex11atm1Sjg/Pex11atm1Sjg,Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008547 abnormal neocortex morphology "any structural anomaly of the larger part of the mammalian cerebral cortex, distinguished from the allocortex by being composed of a larger number of nerve cells arranged in six layers" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.186.211.730.885.213.420]
Show

Allelic Composition: Grin2btm1.1Jlbr/Grin2btm1.1Jlbr,Neurod6tm1(cre)Kan/Neurod6+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: B6.129-Pex11btm1Sjg

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Grin2btm1.1Jlbr/Grin2btm1.1Jlbr,Neurod6tm1(cre)Kan/Neurod6+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: B6.129-Pex11btm1Sjg

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Pex11btm1Sjg/Pex11btm1Sjg
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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