ENSMUSG00000028292


Mus musculus

Features
Gene ID: ENSMUSG00000028292
  
Biological name :Rars2
  
Synonyms : Probable arginine--tRNA ligase, mitochondrial / Q3U186 / Rars2
  
Possible biological names infered from orthology : arginyl-tRNA synthetase 2, mitochondrial / Q5T160
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 34614957
Gene end: 34660167
  
Corresponding Affymetrix probe sets: 10503926 (MoGene1.0st)   1424209_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029968
Ensembl peptide - ENSMUSP00000116173
NCBI entrez gene - 109093     See in Manteia.
MGI - MGI:1923596
RefSeq - XM_017319912
RefSeq - NM_181406
RefSeq - XM_006537548
RefSeq - XM_011249902
RefSeq Peptide - NP_852071
swissprot - A2AT41
swissprot - Q3U186
Ensembl - ENSMUSG00000028292
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rars2ENSDARG00000032277Danio rerio
 RARS2ENSGALG00000015806Gallus gallus
 RARS2ENSG00000146282Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rars / Q9D0I9 / Arginine--tRNA ligase, cytoplasmic / P54136* / arginyl-tRNA synthetase*ENSMUSG0000001884828


Protein motifs (from Interpro)
Interpro ID Name
 IPR001278  Arginine-tRNA ligase
 IPR001412  Aminoacyl-tRNA synthetase, class I, conserved site
 IPR008909  DALR anticodon binding
 IPR009080  Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR035684  Arginyl-tRNA synthetase, catalytic core domain
 IPR036695  Arginyl tRNA synthetase N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006420 arginyl-tRNA aminoacylation IEA
 biological_processGO:0032543 mitochondrial translation IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004814 arginine-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
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Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prkab1tm1a(KOMP)Wtsi/Prkab1tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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