ENSMUSG00000028393


Mus musculus

Features
Gene ID: ENSMUSG00000028393
  
Biological name :Alad
  
Synonyms : Alad / Delta-aminolevulinic acid dehydratase / P10518
  
Possible biological names infered from orthology : aminolevulinate dehydratase / P13716
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: B3
Gene start: 62509169
Gene end: 62519918
  
Corresponding Affymetrix probe sets: 10513608 (MoGene1.0st)   1424877_a_at (Mouse Genome 430 2.0 Array)   1457306_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030090
Ensembl peptide - ENSMUSP00000103068
NCBI entrez gene - 17025     See in Manteia.
MGI - MGI:96853
RefSeq - XM_006537639
RefSeq - NM_001276446
RefSeq - NM_008525
RefSeq Peptide - NP_032551
RefSeq Peptide - NP_001263375
swissprot - P10518
Ensembl - ENSMUSG00000028393
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aladENSDARG00000100372Danio rerio
 ALADENSGALG00000008865Gallus gallus
 ALADENSG00000148218Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001731  Delta-aminolevulinic acid dehydratase
 IPR013785  Aldolase-type TIM barrel
 IPR030656  Delta-aminolevulinic acid dehydratase, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006779 porphyrin-containing compound biosynthetic process IEA
 biological_processGO:0006782 protoporphyrinogen IX biosynthetic process IEA
 biological_processGO:0006783 heme biosynthetic process ISO
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009635 response to herbicide IEA
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0009725 response to hormone IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0010035 response to inorganic substance IEA
 biological_processGO:0010038 response to metal ion IEA
 biological_processGO:0010039 response to iron ion IEA
 biological_processGO:0010043 response to zinc ion IEA
 biological_processGO:0010044 response to aluminum ion IEA
 biological_processGO:0010212 response to ionizing radiation IEA
 biological_processGO:0010266 response to vitamin B1 IEA
 biological_processGO:0010269 response to selenium ion IEA
 biological_processGO:0010288 response to lead ion IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0014823 response to activity IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0032025 response to cobalt ion IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0033014 tetrapyrrole biosynthetic process IEA
 biological_processGO:0033197 response to vitamin E IEA
 biological_processGO:0033273 response to vitamin IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043200 response to amino acid IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0046685 response to arsenic-containing substance IEA
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0046689 response to mercury ion IEA
 biological_processGO:0051260 protein homooligomerization ISO
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0051597 response to methylmercury IEA
 biological_processGO:0070541 response to platinum ion IEA
 biological_processGO:0070542 response to fatty acid IEA
 biological_processGO:0071284 cellular response to lead ion IEA
 biological_processGO:0071353 cellular response to interleukin-4 IDA
 biological_processGO:1901799 negative regulation of proteasomal protein catabolic process ISO
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005839 proteasome core complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004655 porphobilinogen synthase activity ISO
 molecular_functionGO:0008270 zinc ion binding IBA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1904854 proteasome core complex binding IEA


Pathways (from Reactome)
Pathway description
Heme biosynthesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028393 Alad / P10518 / Delta-aminolevulinic acid dehydratase / P13716* / aminolevulinate dehydratase*  / complex






 

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