Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000060	delayed bone ossification	"late onset of the formation of bone" [J:40203]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0000069	kyphoscoliosis	"kyphosis combined with scoliosis" [MGI:CML, J:66943]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0000160	kyphosis	"forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0000259	abnormal vascular development	"malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0000267	abnormal cardiac development	"aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0000269	abnormal looping morphogenesis	"atypical bending of the primitive heart tube during early development" [J:27443]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0000292	distended pericardial sacs	"stretched outer parietal layer of the pericardium" [J:25248]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0000298	absent endocardial cushion	"absence of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal" [MGI:CLS]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0000519	hydronephrosis	"dilation of the pelvis and calices of one or both kidneys" [J:56641]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0000539	distended urinary bladder	"stretched musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0000572	abnormal autopod morphology	"malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0000913	abnormal brain development	"malformed or incomplete differentiation of the brain" [MGI:cls, J:49840]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0000928	incomplete cephalic closure	"arrest of the fusion of the cephalic neural folds" [J:12622]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0000934	abnormal telencephalon development	"malformed or incomplete differentiation of the anterior division of the embryonic prosencephalon " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:49840]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0000960	abnormal sensory ganglia morphology	"malformation or absence of a group of sensory neuron cell bodies" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0000961	abnormal dorsal root ganglia morphology	"malformed group of nerve cell bodies of each segmental nerve projecting from the spinal cord " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:60159]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0000966	reduced sensory neuron number	"fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0000968	abnormal sensory neuron innervation	"defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001002	abnormal taste bud morphology	"anomalous structure of the small sensory organs located in the tongue that contain gustatory receptor cells, basal cells, and supporting cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001008	abnormal sympathetic ganglia morphology	"malformed or absent groups of neuronal cell bodies of the autonomic nervous system" [J:18048]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001011	abnormal superior cervical ganglion morphology	"malformation or absence of the group of neurons that is the largest of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0001015	small superior cervical ganglion	"reduced size of the group of neurons that is the largest of the ganglia of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [J:23882]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001017	abnormal stellate ganglion morphology	"malformation or absence of the group of neurons formed by the fusion of the inferior cervical and first thoracic ganglia" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001052	abnormal muscle innervation	"malfomation or misprojection of sensory or motor nerves to targets in muscle" [J:75958]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001059	optic nerve atrophy	"wasting of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001258	decreased body length	"decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001332	abnormal optic nerve innervation	"misprojection or aberrant target finding of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001344	blepharoptosis	"ptosis, drooping eyelids " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:24414]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001393	ataxia	"inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001412	excessive scratching	"compulsive scraping of the skin, usually with the nails" [J:61340]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001436	abnormal suckling behavior	"reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001441	increased grooming behavior	"increased amount of time spent cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001496	audiogenic seizures	"a reflex seizure triggered by loud noises" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001504	abnormal posture	"atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001513	limb grasping	"mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001698	reduced embryo size	"smaller proportions of embryo compared to littermates" [J:61790]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0001701	incomplete embryo turning	"arrest of the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [J:62571]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0001712	abnormal placental development	"malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001721	absent blood islands	"missing pools of blood in the yolk sac" [J:12623]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0001730	embryonic growth arrest	"the cessation of development beyond a particular stage" [J:17509]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0001852	conjunctivitis	"inflammation of the mucous membrane that lines the inner surface of the eyelids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60896]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0001973	increased thermal nociceptive threshold	"a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0002085	abnormal embryonic tissue morphology	"structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0002229	CNS neurodegeneration	"a retrogressive impairment of function or destruction of neural tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0003203	increased neuron apoptosis	"increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0003229	abnormal vitelline vasculature	"malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0003232	abnormal forebrain development	"anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0003312	abnormal locomotor coordination	"reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0003633	abnormal nervous system physiology		Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0003717	pallor	"an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0003743	abnormal facial morphology	"anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0003793	abnormal submandibular gland morphology	"any structural malformation of either of the large major salivary glands situated beneath the mandible" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0003874	absent branchial arches	"missing the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0003984	embryonic growth retardation	"slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0004069	abnormal muscle spindle morphology	"anomalous structure of the sensory organs in muscle that are involved in the stretch reflex" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004086	absent heartbeat	"lack of a spontaneously beating heart (usually due to defects in the calcium delivery mechanism or loss of a functional contractile apparatus)" [J:69362, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0004200	reduced fetal size	"smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0004201	fetal growth retardation	"slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0004229	abnormal embryonic erythropoiesis	"anomaly in the development of primarily large, nucleated erythroblasts occurring in blood islands in the yolk sac, generally occurs from E7-E11 in the mouse and through 10 weeks in humans" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0004255	abnormal spongiotrophoblast layer morphology	"anomaly in the structure of the outer structural layer of the rodent placenta" [PMID:11433360]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0004259	small placenta	"reduced size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0004573	absent limb buds	"missing the mesenchymal outgrowth on the lateral trunk of the embryo that develops into the limbs" [MESH:National Library of Medicine_Medical Subject Headings]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei
MP:0004783	abnormal cardinal vein morphology	"any structural anomaly of any of the four veins in the developing vertebrate embryo which run along each side of the vertebral column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0004787	abnormal dorsal aorta morphology	"any structural anomaly of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation" [ISBN:0-914294-08-3 "Gray s Anatomy"]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0005302	neurogenic bladder	"defective functioning of the bladder due to impaired innervation, either within the CNS or the PNS" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0005312	pericardial effusion	"escape of fluid from blood vessels or lymphatics into the fibrous sac surrounding the heart" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0005508	abnormal skeleton morphology	"malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0006126	abnormal outflow tract development	"anomaly in the development of the common arterial trunk that forms the aorta and pulmonary artery" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0006222	optic neuropathy	"damage of the optic nerve due to a blockage of its blood supply, to nutritional deficiencies, or to toxins" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0006257	abnormal fungiform papillae	"malformation, absence, or atypical size or shape of the mushroom-shaped papillae, which have a single tase bud at the tip, located mostly on the dorsal anterior portion of the tongue " [smb:Susan M Bello, Mouse Genome Informatics Curator, J:55127]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0006276	abnormal autonomic nervous system physiology	"anomaly in the function of the sensory and motor neurons that run between the central nervous system (especially the hypothalamus and medulla oblongata) and various internal organs (heart, lungs, endocrine and exocrine glands), responsible for controling involuntary bodily functions" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0006294	absent optic vesicle	"absence of the hollow outgrowth from the lateral aspects of the embryonic forebrain from which the retina and optic nerve develop" [J:94391, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0006345	absent second branchial arch	"missing the second branchial arch" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0006404	abnormal lumbar dorsal root ganglion morphology	"any structural anomaly of the group of nerve cell bodies located on the dorsal spinal roots within the vertebral column at the level of the lumbar vertebrae" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0008489	postnatal slow weight gain	"the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0008507	thin retinal ganglion layer	"reduced thickness of the innermost nuclear layer of the retina, which contains neurons that project axons through the optic nerve to the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0008770	decreased survivor rate	"a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0008947	increased neuron number	"greater than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0008948	decreased neuron number	"fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0009289	decreased epididymal fat pad weight		Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0009358	environmentally induced seizures	"relatively mild but sudden stimulation due to changes in ambient habitat including lighting, sounds, touching, and/ or moving cage" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0009431	decreased fetal weight	"reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0009546	absent gastric milk in neonates	"failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0009561	superior cervical ganglion degeneration	"retrogressive pathological change or loss of the largest group of paravertebral ganglia of the sympathetic trunk which normally lies at the base of the skull and innervates the head and neck" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0009674	decreased birth weight	"reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0009703	decreased birth body size	"reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0009937	abnormal neuron differentiation	"abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0010025	decreased total body fat amount	"less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(IKBKAP)#Sasl/0 Genetic Background:* involves: 129S1/Sv * C57BL/6N
MP:0010155	abnormal intestine physiology	"any functional anomaly of the digestive tube passing from the stomach to the anus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1.1Id,Tg(Hsp70-1-cre)6Arge/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * C57BL/6J * CBA
MP:0011087	complete neonatal lethality	"death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J
MP:0011090	partial perinatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Lep^ob/Lep^ob,Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0011098	complete embryonic lethality during organogenesis	"death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Pofut1^cax/Pofut1^cax Genetic Background: involves: C57BL/6J * CAST/Ei Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0012541	absent lamina terminalis	"absence of the anterior-most (rostral) portion of the wall of the neural tube, formed by closure of the anterior neuropore; agenesis of the lamina terminalis results in anencephaly" [MGI:anna]	Show Allelic Composition: Ikbkap^tm1Id/Ikbkap^tm1Id Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: Ikbkap^tm1.1Id/Ikbkap^tm1.1Id Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
MP:0030273	mandibular retrognathia	"abnormal posterior-shifted positioning of the lower jaw (mandible) relative to the facial skeleton and soft tissues" [MGI:anna]	Show Allelic Composition: Ikbkap^{tm1c(KOMP)Wtsi}/Ikbkap^{tm1c(KOMP)Wtsi},H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: C57BL/6J * C57BL/6N * CBA/J

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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