ENSMUSG00000028487


Mus musculus

Features
Gene ID: ENSMUSG00000028487
  
Biological name :Bnc2
  
Synonyms : Bnc2 / Q8BMQ3 / Zinc finger protein basonuclin-2
  
Possible biological names infered from orthology : basonuclin 2 / Q6ZN30
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: C4
Gene start: 84275095
Gene end: 84675275
  
Corresponding Affymetrix probe sets: 10514177 (MoGene1.0st)   1438861_at (Mouse Genome 430 2.0 Array)   1444646_at (Mouse Genome 430 2.0 Array)   1459132_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135778
Ensembl peptide - ENSMUSP00000099884
Ensembl peptide - ENSMUSP00000102816
Ensembl peptide - ENSMUSP00000134774
Ensembl peptide - ENSMUSP00000134795
Ensembl peptide - ENSMUSP00000134942
Ensembl peptide - ENSMUSP00000134953
Ensembl peptide - ENSMUSP00000135089
Ensembl peptide - ENSMUSP00000135283
Ensembl peptide - ENSMUSP00000135375
Ensembl peptide - ENSMUSP00000135411
Ensembl peptide - ENSMUSP00000135480
Ensembl peptide - ENSMUSP00000135499
Ensembl peptide - ENSMUSP00000135569
Ensembl peptide - ENSMUSP00000135580
Ensembl peptide - ENSMUSP00000135607
Ensembl peptide - ENSMUSP00000135656
NCBI entrez gene - 242509     See in Manteia.
MGI - MGI:2443805
RefSeq - XM_017320214
RefSeq - NM_172870
RefSeq - XM_006537933
RefSeq - XM_006537940
RefSeq - XM_017320203
RefSeq - XM_017320204
RefSeq - XM_017320205
RefSeq - XM_017320206
RefSeq - XM_017320207
RefSeq - XM_017320208
RefSeq - XM_017320209
RefSeq - XM_017320210
RefSeq - XM_017320211
RefSeq - XM_017320212
RefSeq - XM_017320213
RefSeq Peptide - NP_766458
swissprot - Q8BMQ3
swissprot - H3BJ03
swissprot - H3BJD5
swissprot - H3BJE5
swissprot - H3BJR1
swissprot - H3BK78
swissprot - H3BKJ2
swissprot - H3BKQ4
swissprot - H3BKR9
swissprot - H3BKX5
swissprot - H3BKY6
swissprot - H3BL10
swissprot - H3BL54
swissprot - H3BLG6
swissprot - H3BIU2
swissprot - H3BIY6
Ensembl - ENSMUSG00000028487
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BNC2ENSG00000173068Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Bnc1 / basonuclin 1 / Q01954*ENSMUSG0000002510541


Protein motifs (from Interpro)
Interpro ID Name
 IPR007527  Zinc finger, SWIM-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003416 endochondral bone growth IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0043586 tongue development IMP
 biological_processGO:0060021 roof of mouth development IMP
 biological_processGO:0060485 mesenchyme development IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000433 microcephaly "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0004420 parietal bone hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, in the curved bone forming part of the vault of the cranium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0004452 abnormal pterygoid process morphology "any structural anomaly of the process projecting downward from either side of the sphenoid bone, in vertebrates divided into two plates, an inner and an outer (sometimes called the lateral and medial); the posterior nares pass through the space, called the pterygoid fossa, between the processes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0004459 small alisphenoid bone "reduced size of either of the broad curved wing like expanses on each side of the sphenoid bone in adults; may exist independently in the young" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0004476 absent palatine bone "absence of either of two irregularly shaped bones that form the back of the hard palate and helps to form the nasal cavity and the floor of the orbits" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0004538 abnormal maxillary shelf "any structural anomaly of the outgrowth of the maxilla that normally fuses with palatine shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0004869 frontal bone hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, in the bone which forms the forehead and roof of the eye orbit" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0009247 meteorism "swelling of the abdomen resulting from gas in the intestinal or peritoneal cavity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0009653 abnormal palate development "abnormal formation of the roof of the mouth in vertebrates formed anteriorly by a bony projection of the upper jaw (hard palate) and posteriorly by the fold of connective tissue (soft palate)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0009888 palatal shelves fail to meet at midline "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0009890 cleft secondary palate "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0009907 decreased tongue size "reduced size of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0030353 wide sagittal suture "an abnormally increased width of the sagittal suture for age-related norms" [MGI:anna]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

 MP:0030387 large posterior fontanelle "an abnormally increased size of the triangle-shaped membranous interval between the pair of parietal bones and the occipital bone for age-related norms; the posterior fontanelle is located at the lambda, at the junction between the sagittal suture and the lambdoid suture" [MGI:anna]
Show

Allelic Composition: Ins2Akita/Ins2Akita
Genetic Background: involves: C57BL/6NSlc

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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