ENSMUSG00000028910


Mus musculus

Features
Gene ID: ENSMUSG00000028910
  
Biological name :Mecr
  
Synonyms : Enoyl-[acyl-carrier-protein] reductase, mitochondrial / Mecr / Q9DCS3
  
Possible biological names infered from orthology : mitochondrial trans-2-enoyl-CoA reductase / Q9BV79
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D2.3
Gene start: 131843470
Gene end: 131867786
  
Corresponding Affymetrix probe sets: 10508686 (MoGene1.0st)   1417097_at (Mouse Genome 430 2.0 Array)   1417098_s_at (Mouse Genome 430 2.0 Array)   1440553_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030742
Ensembl peptide - ENSMUSP00000114543
NCBI entrez gene - 26922     See in Manteia.
MGI - MGI:1349441
RefSeq - XM_011250264
RefSeq - NM_025297
RefSeq - XM_011250261
RefSeq - XM_011250262
RefSeq - XM_011250263
RefSeq - XM_006538885
RefSeq - XM_006538889
RefSeq Peptide - NP_079573
swissprot - Q9DCS3
swissprot - A2A845
Ensembl - ENSMUSG00000028910
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mecrENSDARG00000032326Danio rerio
 MECRENSGALG00000032763Gallus gallus
 MECRENSG00000116353Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Vat1 / Q62465 / vesicle amine transport 1 / Q99536*ENSMUSG0000003499325
Vat1l / Q80TB8 / vesicle amine transport protein 1 like / Q9HCJ6* / vesicle amine transport 1 like*ENSMUSG0000004684423
Cryzl2 / Q3UNZ8 / crystallin zeta like 2ENSMUSG0000003348822
Cryz / P47199 / Quinone oxidoreductase / Q08257* / crystallin zeta*ENSMUSG0000002819922


Protein motifs (from Interpro)
Interpro ID Name
 IPR011032  GroES-like superfamily
 IPR013149  Alcohol dehydrogenase, C-terminal
 IPR013154  Alcohol dehydrogenase, N-terminal
 IPR020843  Polyketide synthase, enoylreductase domain
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process ISO
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016922 nuclear receptor binding ISO
 molecular_functionGO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity IEA


Pathways (from Reactome)
Pathway description
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028910 Mecr / Q9DCS3 / Enoyl-[acyl-carrier-protein] reductase, mitochondrial / Q9BV79* / mitochondrial trans-2-enoyl-CoA reductase*  / complex






 

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contact: otassy@igbmc.fr