ENSMUSG00000029219


Mus musculus

Features
Gene ID: ENSMUSG00000029219
  
Biological name :Slc10a4
  
Synonyms : Q3UEZ8 / Slc10a4 / solute carrier family 10 (sodium/bile acid cotransporter family), member 4
  
Possible biological names infered from orthology : Q96EP9 / solute carrier family 10 member 4
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: C3.2
Gene start: 73006883
Gene end: 73012955
  
Corresponding Affymetrix probe sets: 10522388 (MoGene1.0st)   10530499 (MoGene1.0st)   1433578_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031127
Ensembl peptide - ENSMUSP00000144062
NCBI entrez gene - 231290     See in Manteia.
MGI - MGI:3606480
RefSeq - NM_173403
RefSeq Peptide - NP_775579
swissprot - A2RTJ6
swissprot - A0A0J9YU87
swissprot - Q3UEZ8
Ensembl - ENSMUSG00000029219
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc10a4ENSDARG00000009131Danio rerio
 SLC10A4ENSGALG00000033908Gallus gallus
 Q96EP9ENSG00000145248Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm5868 / Q96EP9* / SLC10A4* / solute carrier family 10 member 4*ENSMUSG0000006020432
O08705 / Slc10a1 / solute carrier family 10 (sodium/bile acid cotransporter family), member 1 / Q14973* / solute carrier family 10 member 1*ENSMUSG0000002113529
P70172 / Slc10a2 / solute carrier family 10, member 2 / Q12908*ENSMUSG0000002307327
Q9CXB2 / Slc10a6 / Solute carrier family 10 member 6 / Q3KNW5*ENSMUSG0000002932125
P21129 / Slc10a3 / solute carrier family 10 (sodium/bile acid cotransporter family), member 3 / P09131* / solute carrier family 10 member 3*ENSMUSG0000003280622
Q5PT54 / Slc10a5 / solute carrier family 10 (sodium/bile acid cotransporter family), member 5 / Q5PT55* / solute carrier family 10 member 5*ENSMUSG0000005892122


Protein motifs (from Interpro)
Interpro ID Name
 IPR002657  Bile acid:sodium symporter/arsenical resistance protein Acr3
 IPR004710  Bile acid:sodium symporter
 IPR030204  Solute carrier family 10 member 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0015721 bile acid and bile salt transport IBA
 biological_processGO:0030534 adult behavior IMP
 biological_processGO:0042493 response to drug IMP
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008508 bile acid:sodium symporter activity IBA
 molecular_functionGO:0015293 symporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm1.1(CAG-Upp1,-GFP)Gp/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * FVB/N

 MP:0002906 susceptibility to pharmacologically induced seizures "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]
Show

Allelic Composition: Gt(ROSA)26Sortm1.1(CAG-Upp1,-GFP)Gp/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * FVB/N

 MP:0008840 abnormal spike wave discharge "anomaly in the characteristic epileptiformic electroencephalographic (EEG) activity detected in generalized absence epilepsy" [PMID:16725200]
Show

Allelic Composition: Gt(ROSA)26Sortm1.1(CAG-Upp1,-GFP)Gp/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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