ENSMUSG00000029246


Mus musculus

Features
Gene ID: ENSMUSG00000029246
  
Biological name :Ppat
  
Synonyms : phosphoribosyl pyrophosphate amidotransferase / Ppat
  
Possible biological names infered from orthology : Q06203
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: C3.3
Gene start: 76913249
Gene end: 76951578
  
Corresponding Affymetrix probe sets: 10530806 (MoGene1.0st)   1428543_at (Mouse Genome 430 2.0 Array)   1441770_at (Mouse Genome 430 2.0 Array)   1452831_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120632
Ensembl peptide - ENSMUSP00000116438
NCBI entrez gene - 231327     See in Manteia.
MGI - MGI:2387203
RefSeq - NM_172146
RefSeq Peptide - NP_742158
swissprot - D6RHB8
swissprot - Q8CIH9
Ensembl - ENSMUSG00000029246
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppatENSDARG00000004517Danio rerio
 PPATENSGALG00000013728Gallus gallus
 PPATENSG00000128059Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000836  Phosphoribosyltransferase domain
 IPR005854  Amidophosphoribosyltransferase
 IPR017932  Glutamine amidotransferase type 2 domain
 IPR029055  Nucleophile aminohydrolases, N-terminal
 IPR029057  Phosphoribosyltransferase-like
 IPR035584  Amidophosphoribosyltransferase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006189 "de novo" IMP biosynthetic process IEA
 biological_processGO:0006543 glutamine catabolic process IEA
 biological_processGO:0007595 lactation IEA
 biological_processGO:0009113 purine nucleobase biosynthetic process IEA
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0009168 purine ribonucleoside monophosphate biosynthetic process IEA
 biological_processGO:0019693 ribose phosphate metabolic process IEA
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IEA
 molecular_functionGO:0004044 amidophosphoribosyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029246 Ppat / phosphoribosyl pyrophosphate amidotransferase / Q06203*  / complex / reaction






 

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