ENSMUSG00000029272


Mus musculus

Features
Gene ID: ENSMUSG00000029272
  
Biological name :Sult1e1
  
Synonyms : Sult1e1
  
Possible biological names infered from orthology : AC108941.2 / P49888 / sulfotransferase family 1E member 1
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E1
Gene start: 87575969
Gene end: 87591594
  
Corresponding Affymetrix probe sets: 10531111 (MoGene1.0st)   1420447_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031201
NCBI entrez gene - 20860     See in Manteia.
MGI - MGI:98431
RefSeq - NM_023135
RefSeq Peptide - NP_075624
swissprot - Q9D566
Ensembl - ENSMUSG00000029272
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011812Gallus gallus
 AC108941.2ENSG00000284695Homo sapiens
 P49888ENSG00000109193Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UZZ6 / Sult1d1 / Sulfotransferase 1 family member D1 ENSMUSG0000002927352
Q9QWG7 / Sult1b1 / Mus musculus sulfotransferase family 1B, member 1 (Sult1b1), transcript variant 1, mRNA. / O43704* / sulfotransferase family 1B member 1*ENSMUSG0000002926948
Q80VR3 / Sult1c1 / Sulfotransferase 1C1 / Q6IMI6* / SULT1C3* / sulfotransferase family 1C member 3*ENSMUSG0000002394347
Q9D939 / Sult1c2 / Sulfotransferase 1C2 / O00338* / sulfotransferase family 1C member 2*ENSMUSG0000002312246
Sult1a1 / sulfotransferase family 1A, phenol-preferring, member 1 / P50226* / P50225* / P0DMM9* / P0DMN0* / SULT1A4* / SULT1A2* / SULT1A3* / sulfotransferase family 1A member 2* / sulfotran...ENSMUSG0000003071143
Sult2a3 / Q06520* / SULT2A1* / sulfotransferase family 2A member 1*ENSMUSG0000007437535
P52843 / Sult2a1 / Bile salt sulfotransferase 1 / Q06520* / sulfotransferase family 2A member 1*ENSMUSG0000007879834
Sult2a4 / sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4 / Q06520* / SULT2A1* / sulfotransferase family 2A member 1*ENSMUSG0000007437734
Sult2a6 / sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6 / Q06520* / SULT2A1* / sulfotransferase family 2A member 1*ENSMUSG0000007081034
Sult2a5 / sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5 / Q06520* / SULT2A1* / sulfotransferase family 2A member 1*ENSMUSG0000007879934
Sult3a1 / sulfotransferase family 3A, member 1ENSMUSG0000006966834
O35400 / Sult2b1 / Sulfotransferase family cytosolic 2B member 1 / O00204* / sulfotransferase family 2B member 1*ENSMUSG0000000327133
Sult2a7 / Q06520* / SULT2A1* / sulfotransferase family 2A member 1*ENSMUSG0000009415632
Sult3a2ENSMUSG0000009029832
Sult2a8 / sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8 / Q06520* / SULT2A1* / sulfotransferase family 2A member 1*ENSMUSG0000003037831
Sult5a1 / sulfotransferase family 5A, member 1ENSMUSG0000000073929


Protein motifs (from Interpro)
Interpro ID Name
 IPR000863  Sulfotransferase domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0008146 sulfotransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Cytosolic sulfonation of small molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0001152 Leydig cell hyperplasia "increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

Allelic Composition: Sult1e1tm1Song/Sult1e1tm1Song
Genetic Background: B6.129S6-Sult1e1tm1Song

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

Allelic Composition: Sult1e1tm1Song/Sult1e1tm1Song
Genetic Background: B6.129S6-Sult1e1tm1Song

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0002786 abnormal Leydig cell morphology "malformation or absence of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0004909 increased seminal gland weight "increase in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0004929 decreased epididymis weight "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0005182 increased circulating estradiol level "greater than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Sult1e1tm1Song/Sult1e1tm1Song
Genetic Background: B6.129S6-Sult1e1tm1Song

 MP:0005464 abnormal platelet physiology "atypical response of the non-nucleated cells found in the blood and involved in blood coagulation" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Sult1e1tm1Song/Sult1e1tm1Song
Genetic Background: B6.129S6-Sult1e1tm1Song

 MP:0012172 abnormal amniotic fluid composition "any alteration in the expected chemical makeup of the watery liquid within the amnion that surrounds and cushions a growing fetus; normally, early in gestation, amniotic fluid is similar to maternal plasma, mainly water with electrolytes, and later in gestation, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid" [MGI:anna]
Show

Allelic Composition: Sult1e1tm1Song/Sult1e1tm1Song
Genetic Background: B6.129S6-Sult1e1tm1Song

 MP:0013598 Leydig cell hypertrophy "increased size of the interstitial cells that are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone (LH)" [MGI:Anna]
Show

Allelic Composition: Igf2tm3Wrk/Igf2+
Genetic Background: Not Specified

 MP:0020407 abnormal placental thrombosis "any anomaly in the formation or presence of a thrombus within the blood vessel network of the placenta" [MGI:anna]
Show

Allelic Composition: Sult1e1tm1Song/Sult1e1tm1Song
Genetic Background: B6.129S6-Sult1e1tm1Song

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029272 Sult1e1 / P49888* / AC108941.2* / sulfotransferase family 1E member 1*  / complex






 

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