ENSMUSG00000029387


Mus musculus

Features
Gene ID: ENSMUSG00000029387
  
Biological name :Gtf2h3
  
Synonyms : Gtf2h3 / Q8VD76 / ral transcription factor IIH subunit 3
  
Possible biological names infered from orthology : general transcription factor IIH subunit 3 / Q13889
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 124579140
Gene end: 124597680
  
Corresponding Affymetrix probe sets: 10525766 (MoGene1.0st)   1454092_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031333
NCBI entrez gene - 209357     See in Manteia.
MGI - MGI:1277143
RefSeq - NM_181410
RefSeq Peptide - NP_852075
swissprot - Q3UZB8
swissprot - Q8VD76
Ensembl - ENSMUSG00000029387
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2h3ENSDARG00000067560Danio rerio
 GTF2H3ENSGALG00000023682Gallus gallus
 GTF2H3ENSG00000111358Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004600  TFIIH subunit Tfb4/GTF2H3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0070816 phosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0000438 core TFIIH complex portion of holo TFIIH complex IEA
 cellular_componentGO:0000439 core TFIIH complex IBA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0005675 holo TFIIH complex IEA
 cellular_componentGO:0097550 transcriptional preinitiation complex IEA
 molecular_functionGO:0003684 damaged DNA binding IBA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA
 molecular_functionGO:0008135 translation factor activity, RNA binding IBA
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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