ENSMUSG00000029417


Mus musculus

Features
Gene ID: ENSMUSG00000029417
  
Biological name :Cxcl9
  
Synonyms : Cxcl9 / C-X-C motif chemokine 9 / P18340
  
Possible biological names infered from orthology : C-X-C motif chemokine ligand 9 / Q07325
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E2
Gene start: 92321347
Gene end: 92328079
  
Corresponding Affymetrix probe sets: 10531407 (MoGene1.0st)   1418652_at (Mouse Genome 430 2.0 Array)   1456907_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108716
NCBI entrez gene - 17329     See in Manteia.
MGI - MGI:1352449
RefSeq - NM_008599
RefSeq Peptide - NP_032625
swissprot - P18340
Ensembl - ENSMUSG00000029417
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CXCL9ENSG00000138755Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cxcl10 / P17515 / C-X-C motif chemokine 10 / P02778* / C-X-C motif chemokine ligand 10*ENSMUSG0000003485526


Protein motifs (from Interpro)
Interpro ID Name
 IPR001089  CXC chemokine
 IPR001811  Chemokine interleukin-8-like domain
 IPR018048  CXC chemokine, conserved site
 IPR027225  CXC chemokine 9
 IPR033899  CXC Chemokine domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002690 positive regulation of leukocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis ISS
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010818 T cell chemotaxis IBA
 biological_processGO:0030816 obsolete positive regulation of cAMP metabolic process IEA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0043950 positive regulation of cAMP-mediated signaling IEA
 biological_processGO:0045663 positive regulation of myoblast differentiation IMP
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:1901741 positive regulation of myoblast fusion IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0048248 CXCR3 chemokine receptor binding IEA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
Show

Allelic Composition: Ctsktm1b(EUCOMM)Hmgu/Ctsktm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Ctsktm1b(EUCOMM)Hmgu/Tcp

 MP:0001805 decreased IgG "less than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arsbtm1Cptr/Arsbtm1Cptr
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0001876 decreased inflammatory response "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arsbtm1Cptr/Arsbtm1Cptr
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0002460 decreased circulating immunoglobulin concentration "less than normal immunoglobulin level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Arsbtm1Cptr/Arsbtm1Cptr
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0003009 abnormal cytokine secretion "impairment or increase of the cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, smb:Susan M. Bello , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arsbtm1Cptr/Arsbtm1Cptr
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: Ctsktm1b(EUCOMM)Hmgu/Ctsktm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Ctsktm1b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000050232 Cxcr3 / O88410 / C-X-C chemokine receptor type 3 / P49682* / C-X-C motif chemokine receptor 3*  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr