ENSG00000138755


Homo sapiens

Features
Gene ID: ENSG00000138755
  
Biological name :CXCL9
  
Synonyms : CXCL9 / C-X-C motif chemokine ligand 9 / Q07325
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q21.1
Gene start: 76001275
Gene end: 76007488
  
Corresponding Affymetrix probe sets: 203915_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000354901
NCBI entrez gene - 4283     See in Manteia.
OMIM - 601704
RefSeq - NM_002416
RefSeq Peptide - NP_002407
swissprot - Q07325
Ensembl - ENSG00000138755
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Cxcl9ENSMUSG00000029417Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CXCL10 / P02778 / C-X-C motif chemokine ligand 10ENSG0000016924529


Protein motifs (from Interpro)
Interpro ID Name
 IPR001089  CXC chemokine
 IPR001811  Chemokine interleukin-8-like domain
 IPR018048  CXC chemokine, conserved site
 IPR027225  CXC chemokine 9
 IPR033899  CXC Chemokine domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002690 positive regulation of leukocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006952 defense response TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0006955 immune response IBA
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010818 T cell chemotaxis IBA
 biological_processGO:0030816 obsolete positive regulation of cAMP metabolic process IDA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0042127 regulation of cell proliferation IDA
 biological_processGO:0043950 positive regulation of cAMP-mediated signaling IDA
 biological_processGO:0045663 positive regulation of myoblast differentiation IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:1901741 positive regulation of myoblast fusion IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 molecular_functionGO:0005125 cytokine activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0048248 CXCR3 chemokine receptor binding IDA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000186810 CXCR3 / P49682 / C-X-C motif chemokine receptor 3  / reaction / complex






 

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