Manteia - Molecule gene

ENSMUSG00000029446

Mus musculus

Features

Gene ID:	ENSMUSG00000029446

Biological name :	Psph

Synonyms :	phosphoserine phosphatase / Psph / Q99LS3

Possible biological names infered from orthology :	P78330

Species:	Mus musculus

Chr. number:	5
Strand:	-1
Band:	G1.3
Gene start:	129765558
Gene end:	129787449

Corresponding Affymetrix probe sets:	10534075 (MoGene1.0st) 10338890 (MoGene1.0st) 10339117 (MoGene1.0st) 10340917 (MoGene1.0st) 10341550 (MoGene1.0st) 10342735 (MoGene1.0st) 10342865 (MoGene1.0st) 10342915 (MoGene1.0st) 10343828 (MoGene1.0st) 10343926 (MoGene1.0st) 10344003 (MoGene1.0st) 10338072 (MoGene1.0st) 10338122 (MoGene1.0st) 10339008 (MoGene1.0st) 10339078 (MoGene1.0st) 10339232 (MoGene1.0st) 10339442 (MoGene1.0st) 10339613 (MoGene1.0st) 10340396 (MoGene1.0st) 10340454 (MoGene1.0st) 10340727 (MoGene1.0st) 10340840 (MoGene1.0st) 10341014 (MoGene1.0st) 10341037 (MoGene1.0st) 10342561 (MoGene1.0st) 10342868 (MoGene1.0st) 10343232 (MoGene1.0st) 10344473 (MoGene1.0st) 1415673_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000031399 Ensembl peptide - ENSMUSP00000144667 Ensembl peptide - ENSMUSP00000116292 Ensembl peptide - ENSMUSP00000113671 NCBI entrez gene - 100678 See in Manteia. MGI - MGI:97788 RefSeq - XM_006504274 RefSeq - XM_017320574 RefSeq - XM_006504275 RefSeq - NM_133900 RefSeq Peptide - NP_598661 swissprot - Q99LS3 swissprot - D3Z666 swissprot - A0A0J9YVH9 swissprot - D3Z4T3 Ensembl - ENSMUSG00000029446

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
psph	ENSDARG00000040314	Danio rerio
PSPH	ENSGALG00000002397	Gallus gallus
PSPH	ENSG00000146733	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

ID

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR023190	Phosphoserine phosphatase, domain 2
IPR023214	HAD superfamily
IPR036412	HAD-like superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006563	L-serine metabolic process	IEA
biological_process	GO:0006564	L-serine biosynthetic process	IEA
biological_process	GO:0008652	cellular amino acid biosynthetic process	IEA
biological_process	GO:0009612	response to mechanical stimulus	IEA
biological_process	GO:0016311	dephosphorylation	IEA
biological_process	GO:0031667	response to nutrient levels	IEA
biological_process	GO:0033574	response to testosterone	IEA
cellular_component	GO:0043005	neuron projection	IEA
molecular_function	GO:0000287	magnesium ion binding	IEA
molecular_function	GO:0004647	phosphoserine phosphatase activity	IEA
molecular_function	GO:0005509	calcium ion binding	IEA
molecular_function	GO:0016787	hydrolase activity	IEA
molecular_function	GO:0042803	protein homodimerization activity	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Serine biosynthesis

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000104	abnormal sphenoid bone morphology	"malformed irregularly shaped bone of the base of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000141	abnormal vertebral body morphology	"malformed main portion of the vertebra anterior to the vertebral canal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000154	rib fusion	"appearance of one or more ribs as a single structure" [J:62022, J:62023]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000186	decreased circulating HDL cholesterol level	"lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0000282	abnormal atrial septum morphology	"abnormality in the wall between the atria of the heart, usually incomplete closure " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000284	double outlet right ventricle	"both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000480	increased number of ribs	"greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi Allelic Composition: Psph^{tm1a(EUCOMM)Hmgu}/Psph⁺ Genetic Background: C57BL/6N-Psph^{tm1a(EUCOMM)Hmgu}/Wtsi
MP:0000559	abnormal femur morphology	"structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000565	oligodactyly	"congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000613	abnormal salivary gland morphology	"malformed saliva-secreting glands of the oral cavity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:63764]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000614	absent salivary gland	"missing any of the saliva-secreting glands of the oral cavity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc, J:54637]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000618	small salivary gland	"reduced size of the saliva-secreting glands of the oral cavity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:63764]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000632	abnormal pineal gland morphology	"anomalous structure of the small, flattened body located in the depression between the superior colliculi and which produces melatonin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000681	abnormal thyroid gland morphology	"anomalous structure of the endocrine gland located in the front and to the sides of the upper part of the trachea and which secretes thyroid hormone and calcitonin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000694	spleen hypoplasia	"small size due to reduced cell number in the spleen" [J:43971]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000703	abnormal thymus morphology	"anomalous structure or development of the primary lymphoid organ; required for immune system development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55400]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000705	athymia	"absence of the primary lymphoid organ" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000757	herniated abdominal wall	"protrusions through and/or into the abdominal wall often resulting in the extrusion of viscera" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0000783	abnormal forebrain morphology	"malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000819	abnormal olfactory bulb morphology	"malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000820	abnormal choroid plexus morphology	"malformed or absent fringe of the tela choroidea of the cerebral ventricles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000841	abnormal hindbrain morphology	"malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0000897	abnormal midbrain	"malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0001015	small superior cervical ganglion	"reduced size of the group of neurons that is the largest of the ganglia of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [J:23882]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0001064	absent trochlear nerve	"missing nerve of the superior oblique muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0001293	anophthalmia	"congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0001297	microphthalmia	"reduced average size of the eyes" [J:18048]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0001303	abnormal lens morphology	"malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0001697	abnormal embryo size	"anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0001722	pale yolk sac	"bloodless yolk sac" [J:62571]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0002015	epithelioid cysts	"abnormal membraneous sacs appearing in an epithelium" [J:51296]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002092	abnormal eye morphology	"abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0002177	abnormal outer ear morphology	"malformation or malfunction of any components of the auricles or external acoustic meatus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002192	hydrops fetalis	"an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0002199	abnormal brain commissure morphology	"absent or defective structure in a bundle of nerve fibers connecting the two brain hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002237	abnormal nasal cavity morphology	"any structural anomaly of the portion of the respiratory tract that extends from the nares to the pharynx; the nasal cavity is lined with ciliated mucosa" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002239	abnormal nasal septum morphology	"any structural anomaly of the structure that separates the two nasal cavities " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002243	abnormal vomeronasal organ morphology	"any structural anomaly of the specialized portion of the nasal septum that is composed of chemosensitive cells and lies anteriorly in the nasal cavity " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002249	abnormal larynx morphology	"any structural anomaly of the most superior portion of the respiratory tract" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002428	abnormal semicircular canal	"anomaly of the organ of balance composed of three long bony tubes of the labyrinth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002633	persistent truncus arteriosis	"complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002697	abnormal eye size	"anomalous bulk of the organ of vision" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0002768	small adrenal glands	"reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0002858	abnormal posterior semicircular canal	"anomaly of the posterior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002928	abnormal bile duct morphology	"malformation of the channels that secrete bile from the liver to the gall bladder and intestines" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0002989	small kidney	"reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0003078	aphakia	"absence of the crystalline lens of the eye" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0003179	decreased platelet count	"fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0003262	intestinal/bowel diverticulum	"a pouch or sac protruding from the intestinal or bowel wall " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0003387	coarctation of aorta	"narrowing of the aorta" [smb:Susan M Bello, Mouse Genome Informatics Curator, ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0003451	absent olfactory bulb	"absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0003686	abnormal eye muscle morphology	"malformation of the muscles of the eye" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0003827	abnormal Wolffian duct morphology	"malformation of the transient embryonic tubes that empty into the cloca and degenerate in the male " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0003928	increased heart rate variability	"increased variation of beat-to-beat intervals of the heart, usually indicitive of a healthy heart" [RGD:Rat Genome Database submission]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0004163	abnormal adenophysis morphology	"any malformation or absence of the anterior part of the pituitary that secretes a variety of hormones; its function is regulated by the hypothalamus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004164	abnormal neurophysis morphology	"any malfomation or absence of the part of the pituitary gland that secretes hormones involved in blood pressure regulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004201	fetal growth retardation	"slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004268	abnormal optic stalk morphology	"any structural anomaly of the narrow, proximal portion of the optic vesicle which connects the embryonic eye and forebrain" [ISBN:0-914294-08-3 "Gray s Anatomy"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004269	abnormal optic cup morphology	"any structural anomaly of double walled stuctured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004509	abnormal pelvic girdle bone morphology	"any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004539	absent maxilla	"missing the upper bony framework of the mouth where the superior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004612	fusion of vertebral bodies	"improper union of the main cylindrical portion of adjacent vertebra ventral to the vertebral canal" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004613	fusion of vertebral arches	"improper union of the dorsal part of adjacent vertebra" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0004666	absent stapedial artery	"absence of the small artery that passes through the ring of the stapes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0005105	abnormal middle ear ossicle morphology	"anomalous structure or development of the three small bones of the middle ear" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0005157	holoprosencephaly	"presence of a single forebrain hemisphere or lobe; often accompanied by a deficit in median facial development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83058]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0005236	abnormal olfactory nerve morphology	"anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0005344	increased circulating bilirubin level	"greater than the normal concentration in the blood of this yellow heme breakdown product" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0005382	craniofacial phenotype		Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0006033	abnormal external auditory canal	"malformation of the canal that connects the outer and middle ear" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:57313]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0006063	abnormal inferior vena cava morphology	"structural malformation in the principal vein draining blood from the lower portion of the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0006254	thin cerebral cortex	"decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0008128	abnormal brain internal capsule morphology	"any structural anomaly of the area of white matter in the brain that lies between the lenticular and caudate nuclei, and contains a group of myelinated ascending and descending axonal fiber tracts that connects the cerebral cortex to the brain stem and spinal cord" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0008129	absent brain internal capsule	"absence of the area of white matter in the brain that lies between the lenticular and caudate nuclei, and contains a group of myelinated ascending and descending axonal fiber tracts that connects the cerebral cortex to the brain stem and spinal cord" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0008923	thoracoschisis	"congenital fissure of the chest wall" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0009688	abnormal spinal cord central canal morphology	"any structural anomaly of the ependyma-lined lumen of the spinal cord that is filled with cerebrospinal fluid; it is patent with the ventricular system of the brain and frequently becomes occluded in aging adults" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0009707	absent external auditory canal	"absence of the canal that connects the outer and middle ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0009771	absent optic chiasm	"absence of the flattened quadrangular body that is the point of crossing of the fibers of the optic nerves" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0009904	tongue hypoplasia	"underdevelopment of the tongue, usually due to a deficiency in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0009905	absent tongue	"absence of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0009931	abnormal skin appearance	"skin that looks different from the usual state" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0010124	decreased bone mineral content	"reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Psen1^{tm1.1(KOMP)Vlcg}/Psen1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psen1^{tm1.1(KOMP)Vlcg}/Ucd
MP:0010418	perimembraneous ventricular septal defect	"abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0010420	muscular ventricular septal defect	"abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0010912	herniated liver	"protrusion of any portion of the liver from its normal anatomical position" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi Allelic Composition: Psph^{tm1.1(KOMP)Vlcg}/Psph^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psph^{tm1.1(KOMP)Vlcg}/Ucd
MP:0013294	prenatal lethality prior to heart atrial septation	"death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]	Show Allelic Composition: Psph^{tm1.1(KOMP)Vlcg}/Psph^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Psph^{tm1.1(KOMP)Vlcg}/Ucd
MP:0013362	absent pineal gland	"absence of the unpaired epithalamic structure that is shaped like a tiny pine cone and located above the posterior commissure near the level of the habenular complex and the sylvian aqueduct; the pineal is both a circumventricular organ and an endocrine organ that secretes melatonin, a serotonin-derived hormone involved in the regulation of circadian rhythms" [MGI:Anna]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013595	absent vomeronasal organ	"lacking the tubular, crescent-sensory organ with a luminal epithelium that contains chemosensitive receptor cells with microvilli that are thought to detect pheromones and transmit signals to the remainder of the accessory olfactory system" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013818	abnormal oral cavity morphology	"any structural anomaly of the anatomical cavity at the start of the digestive tract that is enclosed by the mouth" [UBERON:0000167]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013833	absent olfactory nerve	"absence of the first cranial nerve, which conveys the sense of smell" [MESH:A08.800.800.120.640]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013835	absent hypoglossal nerve	"absence of the motor nerve which innervates all the intrinsic and all but one of the extrinsic muscles of the tongue" [ISBN:0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013836	abnormal hypoglossal nerve topology	"abnormal position of the hypoglossal nerve " [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013840	absent segment of posterior cerebral artery	"absence of a portion of one of a pair of blood vessels that supplies oxygenated blood to the posterior aspect of the brain" [UBERON:0001636]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013842	ductus venosus stenosis	"narrowing of the lumen of the embryonic connection between the portal vein and inferior vena cava formed by the left umbilical vein that allows oxygenated blood to bypass the developing liver during the time when this connection is normally open; this normally closes during develpment to adulthood" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013848	subcutaneous edema	"accumulation of watery or serous fluid in the subcutaneous region below the skin" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013849	absent abducens nerve	"absence of the sixth cranial nerve, which originates in the abducens nucleus of the pons and sends motor fibers to the lateral rectus muscles of the eye" [MESH:A08.800.800.120.030]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013850	absent posterior commissure	"absence of the band of nerve fiber tracts that span the longitudinal fissure beneath the habenula of the pineal body and over the cerebral aqueduct, interconnecting the left and right pretectal regions and some midbrain nuclei" [ISBN:0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013855	absent celiac artery	"absence of the short, thick trunk which arises from the front of the abdominal aorta immediately below the aortic opening in the diaphragm" [ISBN:0-683-40008-8]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013859	abnormal vitelline vein connection	"aberrant or missing attachment of the paired veins that carry blood from the yolk sac back to the embryo" [ISBN:0-683-40008-8, MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013875	trigeminal neuroma		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013878	abnormal ductus venosus valve topology	"abnormal position of the valve present on the right side of the ductus venosus at the site of the junction with the inferior vena cava" [PMID:5438957]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013926	absent neurohypophysis	"absence of the posterior lobe of the pituitary gland" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013927	abnormal facial nerve topology	"abnormal position of the sensory and motor nerve that supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013929	absent eye muscles		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013932	fragmented Meckel s cartilage		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013933	short Meckel s cartilage		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013935	basal brain tissue herniation		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013936	abnormal thymus topology	"of the primary lymphoid organ that is required for maturation of T cells and secretion of thymosins, hormones that stimulate the development of antibodies" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013948	intraembryonal intestine elongation		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013950	abnormal dorsal root ganglion topology	"abnormal position of the dorsal root ganglion in relation to other structures" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013967	abnormal infrahyoid muscle connection		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013970	absent connection between subcutaneous lymph vessels and lymph sac		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013971	blood in lymph vessels		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013980	abnormal pulmonary artery origin		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013988	absent portal vein segment		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013994	abnormal parasellar internal carotid artery branch morphology		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0013996	abnormal vertebral artery origin		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0014009	anastomosis between middle cerebral arteries		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0014019	embryo cyst		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0014021	heterochrony		Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi
MP:0014022	abnormal duodenum topology	"abnormal position of the first division of the small intestine that extends from the pyloris to the junction with the jejunum" [MGI:csmith]	Show Allelic Composition: Izumo1r^{tm2a(KOMP)Wtsi}/Izumo1r^{tm2a(KOMP)Wtsi} Genetic Background: C57BL/6N-Izumo1r^{tm2a(KOMP)Wtsi}/Wtsi

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000029446	Psph / Q99LS3 / phosphoserine phosphatase / P78330*	/ complex

1 s.

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