ENSMUSG00000029472


Mus musculus

Features
Gene ID: ENSMUSG00000029472
  
Biological name :Anapc5
  
Synonyms : Anapc5 / Anaphase-promoting complex subunit 5 / Q8BTZ4
  
Possible biological names infered from orthology : Q9UJX4
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 122787459
Gene end: 122821339
  
Corresponding Affymetrix probe sets: 10533549 (MoGene1.0st)   1416906_at (Mouse Genome 430 2.0 Array)   1433822_x_at (Mouse Genome 430 2.0 Array)   1435177_a_at (Mouse Genome 430 2.0 Array)   1435178_x_at (Mouse Genome 430 2.0 Array)   1453307_a_at (Mouse Genome 430 2.0 Array)   1456695_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142429
Ensembl peptide - ENSMUSP00000143535
Ensembl peptide - ENSMUSP00000143457
Ensembl peptide - ENSMUSP00000143169
Ensembl peptide - ENSMUSP00000143078
Ensembl peptide - ENSMUSP00000143053
Ensembl peptide - ENSMUSP00000142981
Ensembl peptide - ENSMUSP00000142922
Ensembl peptide - ENSMUSP00000142579
Ensembl peptide - ENSMUSP00000083393
Ensembl peptide - ENSMUSP00000142341
NCBI entrez gene - 59008     See in Manteia.
MGI - MGI:1929722
RefSeq - XM_017321048
RefSeq - NM_001042491
RefSeq - NM_001289517
RefSeq - NM_001289518
RefSeq - NM_001289519
RefSeq - NM_001289520
RefSeq - NM_021505
RefSeq - XM_006530429
RefSeq Peptide - NP_001276449
RefSeq Peptide - NP_067480
RefSeq Peptide - NP_001035956
RefSeq Peptide - NP_001276446
RefSeq Peptide - NP_001276447
RefSeq Peptide - NP_001276448
swissprot - A0A0G2JE03
swissprot - A0A0G2JDM7
swissprot - A0A0G2JDE8
swissprot - A0A0G2JG78
swissprot - A0A0G2JFH0
swissprot - A0A0G2JF95
swissprot - A0A0G2JF12
swissprot - Q3TWF7
swissprot - Q3UFC2
swissprot - Q8BTZ4
swissprot - A0A0G2JGE5
Ensembl - ENSMUSG00000029472
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anapc5ENSDARG00000008461Danio rerio
 ANAPC5ENSGALG00000004179Gallus gallus
 ANAPC5ENSG00000089053Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR026000  Anaphase-promoting complex subunit 5 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070979 protein K11-linked ubiquitination ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019903 protein phosphatase binding ISO


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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