ENSMUSG00000029618


Mus musculus

Features
Gene ID: ENSMUSG00000029618
  
Biological name :Ocm
  
Synonyms : Ocm / Oncomodulin / P51879
  
Possible biological names infered from orthology : OCM2 / oncomodulin 2 / P0CE71 / P0CE72
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 144019804
Gene end: 144026670
  
Corresponding Affymetrix probe sets: 10535524 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000082848
Ensembl peptide - ENSMUSP00000106330
Ensembl peptide - ENSMUSP00000031622
NCBI entrez gene - 18261     See in Manteia.
MGI - MGI:97401
RefSeq - NM_033039
RefSeq Peptide - NP_149028
swissprot - D3YXE4
swissprot - P51879
Ensembl - ENSMUSG00000029618
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pvalb8ENSDARG00000037790Danio rerio
 pvalb9ENSDARG00000071601Danio rerio
 OCMENSGALG00000003462Gallus gallus
 OCMENSG00000122543Homo sapiens
 OCM2ENSG00000135175Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pvalb / P32848 / parvalbumin / P20472*ENSMUSG0000000571646


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR008080  Parvalbumin
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0048691 positive regulation of axon extension involved in regeneration IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0051480 regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0070207 protein homotrimerization IEA
 biological_processGO:1902336 positive regulation of retinal ganglion cell axon guidance IEA
 biological_processGO:1905593 positive regulation of optical nerve axon regeneration IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031982 vesicle IEA
 cellular_componentGO:0099512 supramolecular fiber IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001967 deafness "inability to hear" [J:57651]
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Allelic Composition: Clockm1Jt/Clockm1Jt
Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * Jcl:ICR

 MP:0006358 absent pinna reflex "complete failure to respond to an auditory stimulus by a characteristic ear twitch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Grid2ho/Grid2ho
Genetic Background: involves: C57BLKS/J

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Grid2ho/Grid2ho
Genetic Background: involves: C57BLKS/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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