ENSMUSG00000030002


Mus musculus

Features
Gene ID: ENSMUSG00000030002
  
Biological name :Dusp11
  
Synonyms : Dusp11 / Q6NXK5 / RNA/RNP complex-1-interacting phosphatase
  
Possible biological names infered from orthology : dual specificity phosphatase 11 / O75319
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: C3
Gene start: 85942268
Gene end: 85961667
  
Corresponding Affymetrix probe sets: 10545897 (MoGene1.0st)   1452594_at (Mouse Genome 430 2.0 Array)   1454785_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000144380
Ensembl peptide - ENSMUSP00000032071
NCBI entrez gene - 72102     See in Manteia.
MGI - MGI:1919352
RefSeq - NM_028099
RefSeq - XM_017321754
RefSeq Peptide - NP_082375
swissprot - A0A0J9YUX2
swissprot - Q6NXK5
Ensembl - ENSMUSG00000030002
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dusp11ENSDARG00000038156Danio rerio
 ENSGALG00000033014Gallus gallus
 DUSP11ENSG00000144048Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rngtt / O55236 / RNA guanylyltransferase and 5-phosphatase / O60942*ENSMUSG0000002827421


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016070 RNA metabolic process ISO
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0098507 polynucleotide 5" dephosphorylation ISO
 cellular_componentGO:0001650 fibrillar center ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0045171 intercellular bridge ISO
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0004651 polynucleotide 5"-phosphatase activity ISO
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0098519 nucleotide phosphatase activity, acting on free nucleotides ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

 MP:0005543 corneal thinning "decreased thickness of the cornea, the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

 MP:0011965 decreased total retina thickness "decreased width of the retina through the center plane" [MGI:csmith]
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Allelic Composition: Dnase1l2tm1.1(KOMP)Wtsi/Dnase1l2tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnase1l2tm1.1(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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