ENSMUSG00000028274


Mus musculus

Features
Gene ID: ENSMUSG00000028274
  
Biological name :Rngtt
  
Synonyms : O55236 / RNA guanylyltransferase and 5-phosphatase / Rngtt
  
Possible biological names infered from orthology : O60942
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 33310311
Gene end: 33502614
  
Corresponding Affymetrix probe sets: 10503882 (MoGene1.0st)   1425844_a_at (Mouse Genome 430 2.0 Array)   1448714_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029942
Ensembl peptide - ENSMUSP00000103788
NCBI entrez gene - 24018     See in Manteia.
MGI - MGI:1329041
RefSeq - XM_017320189
RefSeq - NM_001305273
RefSeq - NM_011884
RefSeq - XM_006537889
RefSeq - XM_006537890
RefSeq - XM_011250015
RefSeq Peptide - NP_001292202
RefSeq Peptide - NP_036014
swissprot - Q9DCC1
swissprot - O55236
swissprot - Q3UA94
Ensembl - ENSMUSG00000028274
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rngttENSDARG00000032261Danio rerio
 RNGTTENSGALG00000015787Gallus gallus
 RNGTTENSG00000111880Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dusp11 / Q6NXK5 / RNA/RNP complex-1-interacting phosphatase / O75319* / dual specificity phosphatase 11*ENSMUSG0000003000211


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001339  mRNA capping enzyme, catalytic domain
 IPR012340  Nucleic acid-binding, OB-fold
 IPR013846  mRNA capping enzyme, C-terminal
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR017074  mRNA capping enzyme, bifunctional
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006370 7-methylguanosine mRNA capping ISO
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0098507 polynucleotide 5" dephosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004484 mRNA guanylyltransferase activity ISO
 molecular_functionGO:0004651 polynucleotide 5"-phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0008192 RNA guanylyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0050355 triphosphatase activity IEA


Pathways (from Reactome)
Pathway description
mRNA Capping
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000009535 Rnmt / Q9D0L8 / RNA (guanine-7-) methyltransferase / O43148*  / reaction / complex
 ENSMUSG00000002658 Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1 / P35269* / general transcription factor IIF subunit 1*  / reaction / complex
 ENSMUSG00000067995 Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*  / reaction / complex
 ENSMUSG00000003435 Supt5 / O55201 / Transcription elongation factor SPT5 / O00267* / SUPT5H* / SPT5 homolog, DSIF elongation factor subunit*  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr