ENSMUSG00000002658


Mus musculus

Features
Gene ID: ENSMUSG00000002658
  
Biological name :Gtf2f1
  
Synonyms : Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1
  
Possible biological names infered from orthology : general transcription factor IIF subunit 1 / P35269
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: D
Gene start: 57003405
Gene end: 57011288
  
Corresponding Affymetrix probe sets: 10452213 (MoGene1.0st)   1417698_at (Mouse Genome 430 2.0 Array)   1417699_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000002733
NCBI entrez gene - 98053     See in Manteia.
MGI - MGI:1923848
RefSeq - NM_133801
RefSeq - XM_006525194
RefSeq Peptide - NP_598562
swissprot - Q3THK3
Ensembl - ENSMUSG00000002658
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2f1ENSDARG00000032129Danio rerio
 GTF2F1ENSG00000125651Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008851  Transcription initiation factor IIF, alpha subunit
 IPR011039  Transcription Factor IIF, Rap30/Rap74, interaction
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019211 phosphatase activator activity IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:1990841 promoter-specific chromatin binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000046434 P49312 / Hnrnpa1 / Heteroous nuclear ribonucleoprotein A1 Heteroous nuclear ribonucleoprotein A1, N-terminally processed / P09651* / heterogeneous nuclear ribonucleoprotein A1*  / complex / reaction
 ENSMUSG00000009555 Cdk9 / Q99J95 / Cyclin-dependent kinase 9 / P50750*  / complex
 ENSMUSG00000003435 Supt5 / O55201 / Transcription elongation factor SPT5 / O00267* / SUPT5H* / SPT5 homolog, DSIF elongation factor subunit*  / reaction
 ENSMUSG00000022774 Ncbp2 / Q9CQ49 / Nuclear cap-binding protein subunit 2 / P52298*  / complex / reaction
 ENSMUSG00000031585 Gtf2e2 / Q9D902 / ral transcription factor IIE subunit 2 / P29084* / general transcription factor IIE subunit 2*  / complex / reaction
 ENSMUSG00000022828 Gtf2e1 / Q9D0D5 / Mus musculusral transcription factor II E, polypeptide 1 (alpha subunit) (Gtf2e1), transcript variant 2, mRNA. / P29083* / general transcription factor IIE subunit 1*  / reaction / complex
 ENSMUSG00000028330 Ncbp1 / Q3UYV9 / Nuclear cap-binding protein subunit 1 / Q09161*  / reaction / complex
 ENSMUSG00000011960 Ccnt1 / Q9QWV9 / Cyclin-T1 / O60563*  / complex
 ENSMUSG00000019768 Esr1 / P19785 / Estrogen receptor / P03372* / estrogen receptor 1*  / complex
 ENSMUSG00000060475 Wtap / Q9ER69 / Wilms tumour 1-associating protein / Q15007* / WT1 associated protein*  / reaction
 ENSMUSG00000009535 Rnmt / Q9D0L8 / RNA (guanine-7-) methyltransferase / O43148*  / reaction
 ENSMUSG00000024382 Ercc3 / P49135 / TFIIH basal transcription factor complex helicase XPB subunit / P19447* / ERCC excision repair 3, TFIIH core complex helicase subunit*  / reaction
 ENSMUSG00000020962 Gtf2a1 / Q99PM3 / Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA alpha chain Transcription initiation factor IIA beta chain / P52655* / general transcript...  / complex / reaction
 ENSMUSG00000033323 Ctdp1 / Q7TSG2 / RNA polymerase II subunit A C-terminal domain phosphatase / Q9Y5B0* / CTD phosphatase subunit 1*  / reaction
 ENSMUSG00000028274 Rngtt / O55236 / RNA guanylyltransferase and 5-phosphatase / O60942*  / complex / reaction
 ENSMUSG00000028271 Gtf2b / P62915 / Transcription initiation factor IIB / Q00403* / general transcription factor IIB*  / complex / reaction
 ENSMUSG00000028114 Q3UIK4 / Mettl14 / N6-adenosine-methyltransferase non-catalytic subunit / Q9HCE5* / methyltransferase like 14*  / reaction
 ENSMUSG00000067995 Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*  / complex
 ENSMUSG00000033543 Gtf2a2 / Q80ZM7 / Transcription initiation factor IIA subunit 2 / P52657* / general transcription factor IIA subunit 2*  / reaction / complex






 

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