ENSMUSG00000022828


Mus musculus

Features
Gene ID: ENSMUSG00000022828
  
Biological name :Gtf2e1
  
Synonyms : Gtf2e1 / Mus musculusral transcription factor II E, polypeptide 1 (alpha subunit) (Gtf2e1), transcript variant 2, mRNA. / Q9D0D5
  
Possible biological names infered from orthology : general transcription factor IIE subunit 1 / P29083
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B3
Gene start: 37509790
Gene end: 37539789
  
Corresponding Affymetrix probe sets: 10439392 (MoGene1.0st)   1428124_at (Mouse Genome 430 2.0 Array)   1443110_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023525
NCBI entrez gene - 74197     See in Manteia.
MGI - MGI:1921447
RefSeq - XM_006522659
RefSeq - NM_001355727
RefSeq - NM_028812
RefSeq Peptide - NP_083088
RefSeq Peptide - NP_001342656
swissprot - Q9D0D5
Ensembl - ENSMUSG00000022828
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2e1ENSDARG00000000542Danio rerio
 GTF2E1ENSGALG00000042320Gallus gallus
 GTF2E1ENSG00000153767Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002853  Transcription initiation factor IIE subunit alpha, N-terminal
 IPR013137  Zinc finger, TFIIB-type
 IPR017919  Transcription factor TFE/TFIIEalpha HTH domain
 IPR021600  Transcription factor TFIIE alpha subunit, C-terminal
 IPR024550  TFIIEalpha/SarR/Rpc3 HTH domain
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0097550 transcriptional preinitiation complex IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase II Pre-transcription Events
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002658 Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1 / P35269* / general transcription factor IIF subunit 1*  / reaction / complex
 ENSMUSG00000031585 Gtf2e2 / Q9D902 / ral transcription factor IIE subunit 2 / P29084* / general transcription factor IIE subunit 2*  / complex
 ENSMUSG00000067995 Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*  / complex / reaction
 ENSMUSG00000024382 Ercc3 / P49135 / TFIIH basal transcription factor complex helicase XPB subunit / P19447* / ERCC excision repair 3, TFIIH core complex helicase subunit*  / reaction
 ENSMUSG00000020962 Gtf2a1 / Q99PM3 / Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA alpha chain Transcription initiation factor IIA beta chain / P52655* / general transcript...  / reaction / complex
 ENSMUSG00000028271 Gtf2b / P62915 / Transcription initiation factor IIB / Q00403* / general transcription factor IIB*  / complex / reaction
 ENSMUSG00000033543 Gtf2a2 / Q80ZM7 / Transcription initiation factor IIA subunit 2 / P52657* / general transcription factor IIA subunit 2*  / reaction / complex






 

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