ENSG00000153767


Homo sapiens

Features
Gene ID: ENSG00000153767
  
Biological name :GTF2E1
  
Synonyms : general transcription factor IIE subunit 1 / GTF2E1 / P29083
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q13.33
Gene start: 120742637
Gene end: 120783069
  
Corresponding Affymetrix probe sets: 205930_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000283875
Ensembl peptide - ENSP00000418808
Ensembl peptide - ENSP00000417342
Ensembl peptide - ENSP00000417077
NCBI entrez gene - 2960     See in Manteia.
OMIM - 189962
RefSeq - NM_005513
RefSeq - XM_011512745
RefSeq - XM_011512744
RefSeq Peptide - NP_005504
swissprot - E9PER7
swissprot - P29083
swissprot - C9IYL4
swissprot - C9J329
Ensembl - ENSG00000153767
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2e1ENSDARG00000000542Danio rerio
 GTF2E1ENSGALG00000042320Gallus gallus
 Gtf2e1ENSMUSG00000022828Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002853  Transcription initiation factor IIE subunit alpha, N-terminal
 IPR013137  Zinc finger, TFIIB-type
 IPR017919  Transcription factor TFE/TFIIEalpha HTH domain
 IPR021600  Transcription factor TFIIE alpha subunit, C-terminal
 IPR024550  TFIIEalpha/SarR/Rpc3 HTH domain
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0042795 snRNA transcription by RNA polymerase II TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005669 transcription factor TFIID complex IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0097550 transcriptional preinitiation complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
RNA Polymerase II Pre-transcription Events
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000165417 GTF2A1 / P52655 / general transcription factor IIA subunit 1  / reaction / complex
 ENSG00000163161 ERCC3 / P19447 / ERCC excision repair 3, TFIIH core complex helicase subunit  / reaction
 ENSG00000140307 GTF2A2 / P52657 / general transcription factor IIA subunit 2  / reaction / complex
 ENSG00000197265 GTF2E2 / P29084 / general transcription factor IIE subunit 2  / complex
 ENSG00000125651 GTF2F1 / P35269 / general transcription factor IIF subunit 1  / complex / reaction
 ENSG00000188342 GTF2F2 / P13984 / general transcription factor IIF subunit 2  / complex / reaction
 ENSG00000137947 GTF2B / Q00403 / general transcription factor IIB  / reaction / complex






 

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