ENSMUSG00000031585


Mus musculus

Features
Gene ID: ENSMUSG00000031585
  
Biological name :Gtf2e2
  
Synonyms : Gtf2e2 / Q9D902 / ral transcription factor IIE subunit 2
  
Possible biological names infered from orthology : general transcription factor IIE subunit 2 / P29084
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A3
Gene start: 33731833
Gene end: 33777173
  
Corresponding Affymetrix probe sets: 10571288 (MoGene1.0st)   1448884_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140383
Ensembl peptide - ENSMUSP00000132287
Ensembl peptide - ENSMUSP00000141016
Ensembl peptide - ENSMUSP00000141167
Ensembl peptide - ENSMUSP00000126284
Ensembl peptide - ENSMUSP00000129834
NCBI entrez gene - 68153     See in Manteia.
MGI - MGI:1915403
RefSeq - XM_006509188
RefSeq - NM_001167921
RefSeq - NM_001167922
RefSeq - NM_026584
RefSeq - XM_006509185
RefSeq - XM_006509186
RefSeq - XM_006509187
RefSeq Peptide - NP_080860
RefSeq Peptide - NP_001161394
RefSeq Peptide - NP_001161393
swissprot - A0A087WQX6
swissprot - Q9D902
swissprot - A0A087WSS5
swissprot - A0A087WSE8
Ensembl - ENSMUSG00000031585
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2e2ENSDARG00000012672Danio rerio
 GTF2E2ENSGALG00000010283Gallus gallus
 GTF2E2ENSG00000197265Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003166  Transcription factor TFIIE beta subunit, DNA-binding domain
 IPR016656  Transcription initiation factor TFIIE, beta subunit
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0005673 transcription factor TFIIE complex IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RNA Polymerase II Pre-transcription Events
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Fzd4tm1.1(KOMP)Vlcg/Fzd4tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fzd4tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002658 Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1 / P35269* / general transcription factor IIF subunit 1*  / complex / reaction
 ENSMUSG00000022828 Gtf2e1 / Q9D0D5 / Mus musculusral transcription factor II E, polypeptide 1 (alpha subunit) (Gtf2e1), transcript variant 2, mRNA. / P29083* / general transcription factor IIE subunit 1*  / complex
 ENSMUSG00000024382 Ercc3 / P49135 / TFIIH basal transcription factor complex helicase XPB subunit / P19447* / ERCC excision repair 3, TFIIH core complex helicase subunit*  / reaction
 ENSMUSG00000020962 Gtf2a1 / Q99PM3 / Transcription initiation factor IIA subunit 1 Transcription initiation factor IIA alpha chain Transcription initiation factor IIA beta chain / P52655* / general transcript...  / reaction / complex
 ENSMUSG00000028271 Gtf2b / P62915 / Transcription initiation factor IIB / Q00403* / general transcription factor IIB*  / reaction / complex
 ENSMUSG00000067995 Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*  / complex / reaction
 ENSMUSG00000033543 Gtf2a2 / Q80ZM7 / Transcription initiation factor IIA subunit 2 / P52657* / general transcription factor IIA subunit 2*  / complex / reaction






 

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