ENSMUSG00000060475


Mus musculus

Features
Gene ID: ENSMUSG00000060475
  
Biological name :Wtap
  
Synonyms : Q9ER69 / Wilms tumour 1-associating protein / Wtap
  
Possible biological names infered from orthology : Q15007 / WT1 associated protein
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A1
Gene start: 12966796
Gene end: 12992546
  
Corresponding Affymetrix probe sets: 10447897 (MoGene1.0st)   10479268 (MoGene1.0st)   1452401_at (Mouse Genome 430 2.0 Array)   1454805_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125337
Ensembl peptide - ENSMUSP00000124205
Ensembl peptide - ENSMUSP00000125419
Ensembl peptide - ENSMUSP00000007007
Ensembl peptide - ENSMUSP00000123961
Ensembl peptide - ENSMUSP00000124138
NCBI entrez gene - 60532     See in Manteia.
MGI - MGI:1926395
RefSeq - XM_006523341
RefSeq - NM_001113532
RefSeq - NM_001113533
RefSeq - NM_175394
RefSeq Peptide - NP_001107005
RefSeq Peptide - NP_001107004
RefSeq Peptide - NP_780603
swissprot - Q9ER69
swissprot - F7CCI4
swissprot - E0CYH0
swissprot - E0CZF5
Ensembl - ENSMUSG00000060475
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wtapENSDARG00000042642Danio rerio
 WTAPENSGALG00000011660Gallus gallus
 WTAPENSG00000146457Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029732  WTAP/Mum2 family
 IPR033757  Pre-mRNA-splicing regulator WTAP


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0080009 mRNA methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0031965 nuclear membrane ISO
 cellular_componentGO:0036396 RNA N6-methyladenosine methyltransferase complex ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Processing of Capped Intron-Containing Pre-mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gja1Gt(ROSANBetageo)15C3Masn/Gja1Gt(ROSANBetageo)15C3Masn
Genetic Background: involves: 129P2/OlaHsd

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Gja1Gt(ROSANBetageo)15C3Masn/Gja1Gt(ROSANBetageo)15C3Masn
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000022774 Ncbp2 / Q9CQ49 / Nuclear cap-binding protein subunit 2 / P52298*  / reaction
 ENSMUSG00000002658 Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1 / P35269* / general transcription factor IIF subunit 1*  / reaction
 ENSMUSG00000067995 Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*  / reaction
 ENSMUSG00000028114 Q3UIK4 / Mettl14 / N6-adenosine-methyltransferase non-catalytic subunit / Q9HCE5* / methyltransferase like 14*  / complex
 ENSMUSG00000028330 Ncbp1 / Q3UYV9 / Nuclear cap-binding protein subunit 1 / Q09161*  / reaction






 

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