ENSG00000146457


Homo sapiens

Features
Gene ID: ENSG00000146457
  
Biological name :WTAP
  
Synonyms : Q15007 / WT1 associated protein / WTAP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q25.3
Gene start: 159725585
Gene end: 159756319
  
Corresponding Affymetrix probe sets: 1560274_at (Human Genome U133 Plus 2.0 Array)   203137_at (Human Genome U133 Plus 2.0 Array)   210285_x_at (Human Genome U133 Plus 2.0 Array)   214759_at (Human Genome U133 Plus 2.0 Array)   227621_at (Human Genome U133 Plus 2.0 Array)   229630_s_at (Human Genome U133 Plus 2.0 Array)   241626_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000336911
Ensembl peptide - ENSP00000479438
Ensembl peptide - ENSP00000484404
Ensembl peptide - ENSP00000487338
Ensembl peptide - ENSP00000351141
NCBI entrez gene - 9589     See in Manteia.
OMIM - 605442
RefSeq - XM_017011516
RefSeq - NM_001270531
RefSeq - NM_001270532
RefSeq - NM_001270533
RefSeq - NM_004906
RefSeq - NM_152857
RefSeq - NM_152858
RefSeq - XM_017011514
RefSeq - XM_017011515
RefSeq Peptide - NP_001257462
RefSeq Peptide - NP_004897
RefSeq Peptide - NP_690596
RefSeq Peptide - NP_690597
RefSeq Peptide - NP_001257460
RefSeq Peptide - NP_001257461
swissprot - Q15007
swissprot - A0A087X1R4
Ensembl - ENSG00000146457
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wtapENSDARG00000042642Danio rerio
 WTAPENSGALG00000011660Gallus gallus
 WtapENSMUSG00000060475Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029732  WTAP/Mum2 family
 IPR033757  Pre-mRNA-splicing regulator WTAP


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IMP
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0016070 RNA metabolic process TAS
 biological_processGO:0080009 mRNA methylation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0036396 RNA N6-methyladenosine methyltransferase complex IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Processing of Capped Intron-Containing Pre-mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000165819 METTL3 / Q86U44 / methyltransferase like 3  / complex
 ENSG00000188342 GTF2F2 / P13984 / general transcription factor IIF subunit 2  / reaction
 ENSG00000114503 NCBP2 / P52298 / nuclear cap binding protein subunit 2  / reaction
 ENSG00000136937 NCBP1 / Q09161 / nuclear cap binding protein subunit 1  / reaction
 ENSG00000125651 GTF2F1 / P35269 / general transcription factor IIF subunit 1  / reaction
 ENSG00000145388 Q9HCE5 / METTL14 / methyltransferase like 14  / complex






 

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