Manteia

ENSMUSG00000009535

Mus musculus

Features

Gene ID:	ENSMUSG00000009535

Biological name :	Rnmt

Synonyms :	Q9D0L8 / RNA (guanine-7-) methyltransferase / Rnmt

Possible biological names infered from orthology :	O43148

Species:	Mus musculus

Chr. number:	18
Strand:	1
Band:	E2
Gene start:	68300355
Gene end:	68324852

Corresponding Affymetrix probe sets:	10456501 (MoGene1.0st) 1436328_at (Mouse Genome 430 2.0 Array) 1440002_at (Mouse Genome 430 2.0 Array) 1446442_at (Mouse Genome 430 2.0 Array) 1453106_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000123500 Ensembl peptide - ENSMUSP00000025427 Ensembl peptide - ENSMUSP00000117459 Ensembl peptide - ENSMUSP00000122741 Ensembl peptide - ENSMUSP00000009679 NCBI entrez gene - 67897 See in Manteia. MGI - MGI:1915147 RefSeq - XM_011246991 RefSeq - NM_001170953 RefSeq - NM_026440 RefSeq - XM_006526193 RefSeq - XM_006526194 RefSeq - XM_006526196 RefSeq - XM_006526197 RefSeq Peptide - NP_001164424 RefSeq Peptide - NP_080716 swissprot - D3Z4K1 swissprot - D3Z478 swissprot - Q9D0L8 swissprot - D3YYS7 Ensembl - ENSMUSG00000009535

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR004971	mRNA (guanine-N(7))-methyltransferase domain
IPR016899	mRNA (guanine-N(7))-methyltransferase
IPR029063	S-adenosyl-L-methionine-dependent methyltransferase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006370	7-methylguanosine mRNA capping	IBA
biological_process	GO:0006397	mRNA processing	IEA
biological_process	GO:0032259	methylation	IEA
biological_process	GO:0036265	RNA (guanine-N7)-methylation	IBA
biological_process	GO:0106005	RNA 5"-cap (guanine-N7)-methylation	IEA
biological_process	GO:1990830	cellular response to leukemia inhibitory factor	IEP
cellular_component	GO:0001650	fibrillar center	ISO
cellular_component	GO:0005634	nucleus	IBA
cellular_component	GO:0005654	nucleoplasm	ISO
cellular_component	GO:0005845	mRNA cap binding complex	IBA
cellular_component	GO:0031533	mRNA cap methyltransferase complex	ISO
cellular_component	GO:0043235	receptor complex	ISO
molecular_function	GO:0003723	RNA binding	ISO
molecular_function	GO:0004482	mRNA (guanine-N7-)-methyltransferase activity	IBA
molecular_function	GO:0008168	methyltransferase activity	IEA
molecular_function	GO:0016740	transferase activity	IEA

Pathways (from Reactome)

Pathway description

mRNA Capping

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Rad9a^{tm1.1(KOMP)Wtsi}/Rad9a^{tm1.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Rad9a^{tm1.1(KOMP)Wtsi}/Bay

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000003435	Supt5 / O55201 / Transcription elongation factor SPT5 / O00267* / SUPT5H* / SPT5 homolog, DSIF elongation factor subunit*	/ reaction
ENSMUSG00000002658	Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1 / P35269* / general transcription factor IIF subunit 1*	/ reaction
ENSMUSG00000028274	Rngtt / O55236 / RNA guanylyltransferase and 5-phosphatase / O60942*	/ reaction / complex
ENSMUSG00000067995	Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*	/ reaction

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr