ENSG00000101654


Homo sapiens

Features
Gene ID: ENSG00000101654
  
Biological name :RNMT
  
Synonyms : O43148 / RNA guanine-7 methyltransferase / RNMT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: p11.21
Gene start: 13726660
Gene end: 13764558
  
Corresponding Affymetrix probe sets: 202683_s_at (Human Genome U133 Plus 2.0 Array)   202684_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468261
Ensembl peptide - ENSP00000467171
Ensembl peptide - ENSP00000467475
Ensembl peptide - ENSP00000262173
Ensembl peptide - ENSP00000372804
Ensembl peptide - ENSP00000446426
Ensembl peptide - ENSP00000466111
Ensembl peptide - ENSP00000466252
NCBI entrez gene - 8731     See in Manteia.
OMIM - 603514
RefSeq - XM_017026061
RefSeq - NM_003799
RefSeq - XM_005258162
RefSeq - XM_011525749
RefSeq - XM_011525750
RefSeq - XM_011525751
RefSeq - XM_011525753
RefSeq - NM_001308263
RefSeq Peptide - NP_001295192
RefSeq Peptide - NP_003790
swissprot - K7EPP5
swissprot - K7ERH6
swissprot - O43148
swissprot - K7EP06
Ensembl - ENSG00000101654
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnmtENSDARG00000070553Danio rerio
 RNMTENSGALG00000013889Gallus gallus
 RnmtENSMUSG00000009535Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004971  mRNA (guanine-N(7))-methyltransferase domain
 IPR016899  mRNA (guanine-N(7))-methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006370 7-methylguanosine mRNA capping IMP
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0106005 RNA 5"-cap (guanine-N7)-methylation IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005845 mRNA cap binding complex IDA
 cellular_componentGO:0031533 mRNA cap methyltransferase complex IDA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0004482 mRNA (guanine-N7-)-methyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
mRNA Capping
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000111880 RNGTT / O60942 / RNA guanylyltransferase and 5-phosphatase  / reaction / complex
 ENSG00000125651 GTF2F1 / P35269 / general transcription factor IIF subunit 1  / reaction
 ENSG00000188342 GTF2F2 / P13984 / general transcription factor IIF subunit 2  / reaction
 ENSG00000196235 O00267 / SUPT5H / SPT5 homolog, DSIF elongation factor subunit  / reaction






 

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