ENSG00000111880


Homo sapiens

Features
Gene ID: ENSG00000111880
  
Biological name :RNGTT
  
Synonyms : O60942 / RNA guanylyltransferase and 5-phosphatase / RNGTT
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q15
Gene start: 88610272
Gene end: 88963721
  
Corresponding Affymetrix probe sets: 204207_s_at (Human Genome U133 Plus 2.0 Array)   204208_at (Human Genome U133 Plus 2.0 Array)   211387_x_at (Human Genome U133 Plus 2.0 Array)   211849_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358487
Ensembl peptide - ENSP00000358497
Ensembl peptide - ENSP00000442609
NCBI entrez gene - 8732     See in Manteia.
OMIM - 603512
RefSeq - XM_017011402
RefSeq - NM_001286426
RefSeq - NM_001286428
RefSeq - NM_003800
RefSeq - XM_017011401
RefSeq Peptide - NP_003791
RefSeq Peptide - NP_001273355
RefSeq Peptide - NP_001273357
swissprot - O60942
Ensembl - ENSG00000111880
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rngttENSDARG00000032261Danio rerio
 RNGTTENSGALG00000015787Gallus gallus
 RngttENSMUSG00000028274Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DUSP11 / O75319 / dual specificity phosphatase 11ENSG0000014404812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001339  mRNA capping enzyme, catalytic domain
 IPR012340  Nucleic acid-binding, OB-fold
 IPR013846  mRNA capping enzyme, C-terminal
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR017074  mRNA capping enzyme, bifunctional
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006370 7-methylguanosine mRNA capping IDA
 biological_processGO:0006396 RNA processing IDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0098507 polynucleotide 5" dephosphorylation IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004484 mRNA guanylyltransferase activity IDA
 molecular_functionGO:0004651 polynucleotide 5"-phosphatase activity TAS
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0008192 RNA guanylyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0050355 triphosphatase activity IDA


Pathways (from Reactome)
Pathway description
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
mRNA Capping
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101654 RNMT / O43148 / RNA guanine-7 methyltransferase  / reaction / complex
 ENSG00000188342 GTF2F2 / P13984 / general transcription factor IIF subunit 2  / reaction / complex
 ENSG00000196235 O00267 / SUPT5H / SPT5 homolog, DSIF elongation factor subunit  / reaction
 ENSG00000125651 GTF2F1 / P35269 / general transcription factor IIF subunit 1  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr