ENSDARG00000032261


Danio rerio

Features
Gene ID: ENSDARG00000032261
  
Biological name :rngtt
  
Synonyms : Q6NY98 / RNA guanylyltransferase and 5-phosphatase / rngtt
  
Possible biological names infered from orthology : O55236 / O60942
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 943879
Gene end: 1120056
  
Corresponding Affymetrix probe sets: Dr.25902.1.A1_at (Zebrafish Array)   NM_212867_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040679
NCBI entrez gene - 405803     See in Manteia.
RefSeq - NM_212867
RefSeq Peptide - NP_998032
swissprot - Q6NY98
ZFIN ID - ZDB-GENE-040426-2087
Ensembl - ENSDARG00000032261
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RNGTTENSGALG00000015787Gallus gallus
 RNGTTENSG00000111880Homo sapiens
 RngttENSMUSG00000028274Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dusp11 / dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) / O75319* / Q6NXK5* / dual specificity phosphatase 11* / RNA/RNP complex-1-interacting phosphatase *ENSDARG0000003815613


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR001339  mRNA capping enzyme, catalytic domain
 IPR012340  Nucleic acid-binding, OB-fold
 IPR013846  mRNA capping enzyme, C-terminal
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR017074  mRNA capping enzyme, bifunctional
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006370 7-methylguanosine mRNA capping ISS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0098507 polynucleotide 5" dephosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004484 mRNA guanylyltransferase activity ISS
 molecular_functionGO:0004651 polynucleotide 5"-phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0050355 triphosphatase activity ISS


Pathways (from Reactome)
Pathway description
mRNA Capping
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
Show

 ZFA:0001114 head head decreased width , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042724 supt5h / SPT5 homolog, DSIF elongation factor subunit / Supt5* / O55201* / O00267* / Transcription elongation factor SPT5 *  / reaction
 ENSDARG00000069910 gtf2f2a / general transcription factor IIF, polypeptide 2a / GTF2F2* / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 * / general transcription factor IIF subunit 2*  / complex / reaction
 ENSDARG00000006816 gtf2f2b / general transcription factor IIF, polypeptide 2b / GTF2F2* / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 * / general transcription factor IIF subunit 2*  / reaction / complex
 ENSDARG00000070553 rnmt / Q1MTD3 / RNA (guanine-7-) methyltransferase / O43148* / Q9D0L8*  / complex / reaction






 

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