ENSDARG00000069910


Danio rerio

Features
Gene ID: ENSDARG00000069910
  
Biological name :gtf2f2a
  
Synonyms : general transcription factor IIF, polypeptide 2a / gtf2f2a
  
Possible biological names infered from orthology : general transcription factor IIF subunit 2 / GTF2F2 / P13984 / Q8R0A0 / ral transcription factor IIF subunit 2
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 34695373
Gene end: 34706903
  
Corresponding Affymetrix probe sets: Dr.5240.1.S1_at (Zebrafish Array)   Dr.5240.2.S1_a_at (Zebrafish Array)   NM_001002127_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000092894
Ensembl peptide - ENSDARP00000124240
Ensembl peptide - ENSDARP00000113068
Ensembl peptide - ENSDARP00000072210
NCBI entrez gene - 415217     See in Manteia.
RefSeq - NM_001002127
RefSeq Peptide - NP_001002127
swissprot - B8JHR3
swissprot - A7MCQ3
swissprot - F8W4C3
ZFIN ID - ZDB-GENE-040625-131
Ensembl - ENSDARG00000069910
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GTF2F2ENSGALG00000016974Gallus gallus
 GTF2F2ENSG00000188342Homo sapiens
 Gtf2f2ENSMUSG00000067995Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gtf2f2b / general transcription factor IIF, polypeptide 2b / GTF2F2* / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 * / general transcription factor IIF subunit 2*ENSDARG0000000681675


Protein motifs (from Interpro)
Interpro ID Name
 IPR003196  Transcription initiation factor IIF, beta subunit
 IPR011039  Transcription Factor IIF, Rap30/Rap74, interaction
 IPR011991  ArsR-like helix-turn-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IBA
 biological_processGO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005674 transcription factor TFIIF complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000991 transcription factor activity, core RNA polymerase II binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000000542 gtf2e1 / general transcription factor IIE, polypeptide 1, alpha / P29083* / Q9D0D5* / general transcription factor IIE subunit 1* / Mus musculusral transcription factor II E, polypeptide 1 ...  / complex / reaction
 ENSDARG00000012672 gtf2e2 / general transcription factor IIE, polypeptide 2, beta / P29084* / Q9D902* / ral transcription factor IIE subunit 2 * / general transcription factor IIE subunit 2*  / complex / reaction
 ENSDARG00000012827 F1R777 / mettl3 / methyltransferase like 3 / Q86U44*  / reaction
 ENSDARG00000032261 rngtt / Q6NY98 / RNA guanylyltransferase and 5-phosphatase / O55236* / O60942*  / reaction / complex
 ENSDARG00000070553 rnmt / Q1MTD3 / RNA (guanine-7-) methyltransferase / O43148* / Q9D0L8*  / reaction
 ENSDARG00000042642 wtap / Q7SXL7 / WT1 associated protein / Q9ER69* / Q15007* / Wilms tumour 1-associating protein*  / reaction
 ENSDARG00000053685 gtf2a2 / general transcription factor IIA, 2 / P52657* / Q80ZM7* / general transcription factor IIA subunit 2* / Transcription initiation factor IIA subunit 2 *  / reaction / complex
 ENSDARG00000014898 ncbp2 / Q8JGR6 / nuclear cap binding protein subunit 2 / Q9CQ49* / NCBP2L* / P52298* / A6PVI3* / nuclear cap binding protein subunit 2 like*  / complex
 ENSDARG00000042724 supt5h / SPT5 homolog, DSIF elongation factor subunit / Supt5* / O55201* / O00267* / Transcription elongation factor SPT5 *  / reaction
 ENSDARG00000044811 cdk9 / cyclin-dependent kinase 9 (CDC2-related kinase) / P50750* / Q99J95* / cyclin dependent kinase 9*  / complex
 ENSDARG00000004111 esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *  / complex
 ENSDARG00000070278 Q6NZ22 / mettl14 / methyltransferase like 14 / Q9HCE5* / Q3UIK4* / N6-adenosine-methyltransferase non-catalytic subunit *  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr