ENSMUSG00000033323


Mus musculus

Features
Gene ID: ENSMUSG00000033323
  
Biological name :Ctdp1
  
Synonyms : Ctdp1 / Q7TSG2 / RNA polymerase II subunit A C-terminal domain phosphatase
  
Possible biological names infered from orthology : CTD phosphatase subunit 1 / Q9Y5B0
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: E3
Gene start: 80407959
Gene end: 80469695
  
Corresponding Affymetrix probe sets: 10459930 (MoGene1.0st)   1452697_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038938
Ensembl peptide - ENSMUSP00000123705
NCBI entrez gene - 67655     See in Manteia.
MGI - MGI:1926953
RefSeq - XM_011247096
RefSeq - NM_026295
RefSeq - XM_006526525
RefSeq - XM_006526526
RefSeq Peptide - NP_080571
swissprot - E0CZ13
swissprot - Q7TSG2
Ensembl - ENSMUSG00000033323
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctdp1ENSDARG00000017522Danio rerio
 CTDP1ENSGALG00000031461Gallus gallus
 CTDP1ENSG00000060069Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR004274  FCP1 homology domain
 IPR011053  Single hybrid motif
 IPR011947  FCP1-like phosphatase, phosphatase domain
 IPR015388  FCP1-like phosphatase, C-terminal
 IPR023214  HAD superfamily
 IPR036412  HAD-like superfamily
 IPR036420  BRCT domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010458 exit from mitosis IEA
 biological_processGO:0043923 positive regulation by host of viral transcription IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0061052 negative regulation of cell growth involved in cardiac muscle cell development IEA
 biological_processGO:0070940 dephosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0000922 spindle pole ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016591 DNA-directed RNA polymerase II, holoenzyme IBA
 cellular_componentGO:0030496 midbody ISO
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0051233 spindle midzone IEA
 molecular_functionGO:0001096 TFIIF-class transcription factor binding IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008420 CTD phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030957 Tat protein binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003435 Supt5 / O55201 / Transcription elongation factor SPT5 / O00267* / SUPT5H* / SPT5 homolog, DSIF elongation factor subunit*  / reaction / complex
 ENSMUSG00000028330 Ncbp1 / Q3UYV9 / Nuclear cap-binding protein subunit 1 / Q09161*  / reaction / complex
 ENSMUSG00000067995 Gtf2f2 / Q8R0A0 / ral transcription factor IIF subunit 2 / P13984* / general transcription factor IIF subunit 2*  / reaction
 ENSMUSG00000022774 Ncbp2 / Q9CQ49 / Nuclear cap-binding protein subunit 2 / P52298*  / complex / reaction
 ENSMUSG00000002658 Gtf2f1 / Q3THK3 / ral transcription factor IIF subunit 1 / P35269* / general transcription factor IIF subunit 1*  / reaction
 ENSMUSG00000029111 Nelfa / Q8BG30 / Negative elongation factor A / Q9H3P2* / negative elongation factor complex member A*  / complex / reaction
 ENSMUSG00000020485 P63271 / Supt4a / suppressor of Ty 4A / P63272* / SUPT4H1* / SPT4 homolog, DSIF elongation factor subunit*  / complex / reaction
 ENSMUSG00000024369 Nelfe / P19426 / negative elongation factor complex member E, Rdbp / P18615* / negative elongation factor complex member E*  / reaction / complex






 

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