ENSMUSG00000030682


Mus musculus

Features
Gene ID: ENSMUSG00000030682
  
Biological name :Cdipt
  
Synonyms : Cdipt / CDP-diacylglycerol--inositol 3-phosphatidyltransferase / Q8VDP6
  
Possible biological names infered from orthology : O14735
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F3
Gene start: 126975914
Gene end: 126980501
  
Corresponding Affymetrix probe sets: 10557560 (MoGene1.0st)   1423657_at (Mouse Genome 430 2.0 Array)   1436715_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145579
Ensembl peptide - ENSMUSP00000146256
Ensembl peptide - ENSMUSP00000146137
Ensembl peptide - ENSMUSP00000145918
Ensembl peptide - ENSMUSP00000145841
Ensembl peptide - ENSMUSP00000145787
Ensembl peptide - ENSMUSP00000032920
NCBI entrez gene - 52858     See in Manteia.
MGI - MGI:105491
RefSeq - XM_017322360
RefSeq - NM_026638
RefSeq - XM_006508022
RefSeq Peptide - NP_001334585
RefSeq Peptide - NP_080914
swissprot - A0A0U1RQ57
swissprot - Q05BY1
swissprot - Q8VDP6
swissprot - A0A0U1RP60
swissprot - A0A0U1RNI6
swissprot - A0A0U1RP13
swissprot - A0A0U1RPV3
Ensembl - ENSMUSG00000030682
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdiptENSDARG00000070686Danio rerio
 CDIPTENSG00000103502Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000462  CDP-alcohol phosphatidyltransferase
 IPR014387  CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006661 phosphatidylinositol biosynthetic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 biological_processGO:0046341 CDP-diacylglycerol metabolic process IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016780 phosphotransferase activity, for other substituted phosphate groups IEA
 molecular_functionGO:0019992 diacylglycerol binding IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0043178 alcohol binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PI


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003898 abnormal QRS complex "anomaly in the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarise prior to their contraction" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

 MP:0011972 decreased circulating lactate dehydrogenase level "reduced blood level of the tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of lactate and pyruvate; measurements of circulating levels are used clinically as a diagnostic indicator of tissue breakdown, some forms of cancer or particular infection types" [MeSH:D08.811.682.047.551.400, MGI:csmith]
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Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
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Allelic Composition: Cbx2tm1b(KOMP)Wtsi/Cbx2+
Genetic Background: C57BL/6N-Cbx2tm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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