ENSMUSG00000030726


Mus musculus

Features
Gene ID: ENSMUSG00000030726
  
Biological name :Pold3
  
Synonyms : Pold3 / polymerase (DNA-directed), delta 3, accessory subunit
  
Possible biological names infered from orthology : DNA polymerase delta 3, accessory subunit / Q15054
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E2
Gene start: 100082111
Gene end: 100121565
  
Corresponding Affymetrix probe sets: 10565862 (MoGene1.0st)   1426838_at (Mouse Genome 430 2.0 Array)   1426839_at (Mouse Genome 430 2.0 Array)   1443733_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032969
Ensembl peptide - ENSMUSP00000146986
Ensembl peptide - ENSMUSP00000146603
Ensembl peptide - ENSMUSP00000146431
Ensembl peptide - ENSMUSP00000115707
NCBI entrez gene - 67967     See in Manteia.
MGI - MGI:1915217
RefSeq - XM_017312275
RefSeq - NM_133692
RefSeq - XM_006508149
RefSeq - XM_006508150
RefSeq Peptide - NP_598453
swissprot - D6RG54
swissprot - Q8BH76
swissprot - A0A140LHY7
swissprot - A0A140LHJ0
swissprot - A0A140LIW6
Ensembl - ENSMUSG00000030726
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pold3ENSDARG00000076169Danio rerio
 POLD3ENSGALG00000017307Gallus gallus
 POLD3ENSG00000077514Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019038  DNA polymerase subunit Cdc27


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006297 nucleotide-excision repair, DNA gap filling IEA
 cellular_componentGO:0005634 nucleus IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Removal of the Flap Intermediate from the C-strand
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching
Removal of the Flap Intermediate
Processive synthesis on the lagging strand


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

 MP:0013294 prenatal lethality prior to heart atrial septation "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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