ENSMUSG00000030965


Mus musculus

Features
Gene ID: ENSMUSG00000030965
  
Biological name :Abraxas2
  
Synonyms : Abraxas2 / BRISC complex subunit
  
Possible biological names infered from orthology : abraxas 2, BRISC complex subunit / Q15018
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F3
Gene start: 132859225
Gene end: 132885111
  
Corresponding Affymetrix probe sets: 10558274 (MoGene1.0st)   1433846_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000081541
Ensembl peptide - ENSMUSP00000147850
Ensembl peptide - ENSMUSP00000120309
Ensembl peptide - ENSMUSP00000116254
Ensembl peptide - ENSMUSP00000101767
NCBI entrez gene - 109359     See in Manteia.
MGI - MGI:1926116
RefSeq - NM_198017
RefSeq Peptide - NP_932134
swissprot - A0A1B0GS96
swissprot - D6RJ39
swissprot - Z4YJY0
swissprot - D6RHR6
swissprot - D3Z4D8
Ensembl - ENSMUSG00000030965
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abraxas2bENSDARG00000098907Danio rerio
 FAM175BENSGALG00000038054Gallus gallus
 Q15018ENSG00000165660Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BPZ8 / Abraxas1 / BRCA1 A complex subunit / Q6UWZ7* / abraxas 1, BRCA1 A complex subunit*ENSMUSG0000003523428


Protein motifs (from Interpro)
Interpro ID Name
 IPR023238  FAM175 family
 IPR023240  FAM175 family, BRISC complex, Abro1 subunit
 IPR037518  MPN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0008608 attachment of spindle microtubules to kinetochore IEA
 biological_processGO:0070536 protein K63-linked deubiquitination IEA
 biological_processGO:0090307 mitotic spindle assembly IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0031616 spindle pole centrosome IEA
 cellular_componentGO:0036449 microtubule minus-end IEA
 cellular_componentGO:0070552 BRISC complex IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Metalloprotease DUBs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000218 increased WBC count "greater than normal WBC numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Epb41tm1b(KOMP)Mbp/Epb41+
Genetic Background: C57BL/6N-Epb41tm1b(KOMP)Mbp/J

 MP:0005477 increased circulating thyroxine level "greater than the normal blood concentration of the major hormone dervied from the thryoid gland; it normally affects cellular metabolism" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Epb41tm1b(KOMP)Mbp/Epb41+
Genetic Background: C57BL/6N-Epb41tm1b(KOMP)Mbp/J

 MP:0005505 increased platelet count "greater than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Epb41tm1b(KOMP)Mbp/Epb41+
Genetic Background: C57BL/6N-Epb41tm1b(KOMP)Mbp/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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