ENSG00000165660


Homo sapiens

Features
Gene ID: ENSG00000165660
  
Biological name :ABRAXAS2
  
Synonyms : ABRAXAS2 / abraxas 2, BRISC complex subunit / Q15018
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.13
Gene start: 124801785
Gene end: 124836670
  
Corresponding Affymetrix probe sets: 212835_at (Human Genome U133 Plus 2.0 Array)   212837_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000298492
NCBI entrez gene - 23172     See in Manteia.
OMIM - 611144
RefSeq - XM_017015986
RefSeq - NM_032182
RefSeq - XM_011539554
RefSeq Peptide - NP_115558
swissprot - Q15018
Ensembl - ENSG00000165660
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abraxas2bENSDARG00000098907Danio rerio
 FAM175BENSGALG00000038054Gallus gallus
 Abraxas2ENSMUSG00000030965Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6UWZ7 / ABRAXAS1 / abraxas 1, BRCA1 A complex subunitENSG0000016332228


Protein motifs (from Interpro)
Interpro ID Name
 IPR023238  FAM175 family
 IPR023240  FAM175 family, BRISC complex, Abro1 subunit
 IPR037518  MPN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0002931 response to ischemia IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0008608 attachment of spindle microtubules to kinetochore IMP
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070536 protein K63-linked deubiquitination IMP
 biological_processGO:0090307 mitotic spindle assembly IMP
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0030496 midbody IDA
 cellular_componentGO:0031616 spindle pole centrosome IDA
 cellular_componentGO:0036449 microtubule minus-end IDA
 cellular_componentGO:0070552 BRISC complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IDA


Pathways (from Reactome)
Pathway description
Metalloprotease DUBs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000185515 BRCC3 / P46736 / BRCA1/BRCA2-containing complex subunit 3  / complex
 ENSG00000162711 NLRP3 / Q96P20 / NLR family pyrin domain containing 3  / complex
 ENSG00000158019 BABAM2 / Q9NXR7 / BRISC and BRCA1 A complex member 2  / complex
 ENSG00000105393 BABAM1 / Q9NWV8 / BRISC and BRCA1 A complex member 1  / complex






 

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