ENSMUSG00000031232


Mus musculus

Features
Gene ID: ENSMUSG00000031232
  
Biological name :Magt1
  
Synonyms : magnesium transporter 1 / Magt1
  
Possible biological names infered from orthology : Q9H0U3
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: D
Gene start: 105968084
Gene end: 106011906
  
Corresponding Affymetrix probe sets: 10606301 (MoGene1.0st)   1419459_a_at (Mouse Genome 430 2.0 Array)   1428624_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120994
Ensembl peptide - ENSMUSP00000033583
Ensembl peptide - ENSMUSP00000109196
Ensembl peptide - ENSMUSP00000115579
NCBI entrez gene - 67075     See in Manteia.
MGI - MGI:1914325
RefSeq - NM_025952
RefSeq - NM_001190409
RefSeq Peptide - NP_080228
RefSeq Peptide - NP_001177338
swissprot - F6TBV1
swissprot - A2ADH1
swissprot - F6WHL0
Ensembl - ENSMUSG00000031232
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 magt1ENSDARG00000058062Danio rerio
 MAGT1ENSGALG00000007861Gallus gallus
 MAGT1ENSG00000102158Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tusc3 / Q8BTV1 / tumor suppressor candidate 3 / Q13454*ENSMUSG0000003953061


Protein motifs (from Interpro)
Interpro ID Name
 IPR006844  Magnesium transporter protein 1
 IPR021149  Oligosaccharyl transferase complex, subunit OST3/OST6
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Miscellaneous transport and binding events
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Foxp1tm1.1Pwt/Foxp1tm1.1Pwt,Foxp4tm2.1Eem/Foxp4tm2.1Eem,Scgb1a1tm1(icre)Fjd/Scgb1a1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Magt1Gt(OST199678)Lex/Y
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

 MP:0004939 abnormal B cell morphology "any structural anomaly of lymphocytes that expresses membrane-bound immunoglobulin complexes in the mature form, and differentiate into antibody-secreting plasma cells and memory cells upon interaction with antigen; B cells are the primary lymphocyte responsible for humoral immunity, and are most effective against extracellular pathogens" [CL:0000236, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hmcesem2Dfel/Hmces+
Genetic Background: involves: 129 * C57BL/6N

 MP:0005014 increased B cell number "greater than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Hmcesem2Dfel/Hmces+
Genetic Background: involves: 129 * C57BL/6N

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Hmcesem2Dfel/Hmces+
Genetic Background: involves: 129 * C57BL/6N

 MP:0005154 increased B cell proliferation "greater than the normal response by B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Hmcesem2Dfel/Hmces+
Genetic Background: involves: 129 * C57BL/6N

 MP:0008098 decreased plasma cell number "reduced number of terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin" [CL:0000786, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hmcesem2Dfel/Hmces+
Genetic Background: involves: 129 * C57BL/6N

 MP:0008181 increased marginal zone B cell number "greater number of CD23-negative, CD21-positive B cells of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL" [CL:0000845, ISBN:0781735149]
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Allelic Composition: Hmcesem2Dfel/Hmces+
Genetic Background: involves: 129 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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