Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000120	malocclusion	"perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509]	Show Allelic Composition: Mecp2^tm1Pplt/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum4^M1Jus/Sum4⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0000160	kyphosis	"forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
MP:0000182	increased circulating LDL cholesterol level	"greater than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0000418	patchy hair	"uneven spots of hair growth on the body" [J:26975]	Show Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy
MP:0000420	ruffled hair	"fuzzy, irregular appearance of the hair" [J:50844]	Show Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6
MP:0000454	abnormal jaw morphology	"malformation of the bony framework of the mouth where the teeth are held" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Olfr17^{tm4(Olfr6)Rax}/Olfr17⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000745	tremors	"repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Ins2^Akita/Ins2⁺ Genetic Background: C57BL/6-Ins2^Akita/J Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: 129S7/SvEvBrd-Mecp2^tm1Hzo Allelic Composition: Mecp2^tm1Hzo/Mecp2⁺ Genetic Background: 129S7/SvEvBrd-Mecp2^tm1Hzo Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺,Tg(CAG-cre/Esr1)5Amc/? Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Y,Tg(CAG-cre/Esr1)5Amc/0 Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2G273X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum1^M1Jus/Sum1⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum2^M1Jus/Sum2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum4^M1Jus/Sum4⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum5^M1Jus/Sum5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0000774	reduced brain size	"smaller appearance of the brain" [J:35802]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N
MP:0000788	abnormal cerebral cortex morphology	"malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2G273X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB
MP:0000807	abnormal hippocampus morphology	"absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock Allelic Composition: Mecp2^tm1Vnar/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl Allelic Composition: Mecp2^tm1.1Vnar/Mecp2^tm1.1Vnar Genetic Background: B6N.129-Mecp2^tm1.1Vnar Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2G273X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB
MP:0000812	abnormal dentate gyrus morphology	"absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857]	Show Allelic Composition: Mecp2^tm1Vnar/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl Allelic Composition: Mecp2^tm1.1Vnar/Mecp2^tm1.1Vnar Genetic Background: B6N.129-Mecp2^tm1.1Vnar
MP:0000819	abnormal olfactory bulb morphology	"malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461]	Show Allelic Composition: Mecp2^tm1Vnar/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl Allelic Composition: Mecp2^tm1.1Vnar/Mecp2^tm1.1Vnar Genetic Background: B6N.129-Mecp2^tm1.1Vnar Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0000849	abnormal cerebellum morphology	"any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Mecp2^tm1Vnar/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl Allelic Composition: Mecp2^tm1.1Vnar/Mecp2^tm1.1Vnar Genetic Background: B6N.129-Mecp2^tm1.1Vnar
MP:0000886	abnormal cerebellar granule layer	"any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Mecp2^tm1Vnar/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl Allelic Composition: Mecp2^tm1.1Vnar/Mecp2^tm1.1Vnar Genetic Background: B6N.129-Mecp2^tm1.1Vnar
MP:0000913	abnormal brain development	"malformed or incomplete differentiation of the brain" [MGI:cls, J:49840]	Show Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2G273X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB
MP:0000951	sporadic seizures	"occasional seizures occuring at irregular intervals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001194	dermatitis	"inflammation of the skin" [J:65146]	Show Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum2^M1Jus/Sum2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum4^M1Jus/Sum4⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
MP:0001212	skin lesions	"focal patches of inflammation on the skin" [J:30162]	Show Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy
MP:0001259	abnormal body weight	"anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Eomes^{tm1.1(cre/ERT2)Sjar}/Eomes⁺ Genetic Background: involves: 129S/SvEv Allelic Composition: Mecp2^tm1.1Bird/Y,Sum2^M1Jus/Sum2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum5^M1Jus/Sum5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * 129/SvJ
MP:0001260	increased body weight	"greater than normal average weight " [J:33400]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x C57BL/6)F1 Allelic Composition: Mecp2^tm2.1Jae/Y Genetic Background: involves: 129/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Joez/Mecp2⁺ Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2G273X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0001261	obese	"excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm2Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺,Tg(CAG-cre/Esr1)5Amc/? Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * 129/SvJ
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Mapt^{tm1(Mecp2)Jae}/Mapt⁺ Genetic Background: involves: 129/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL Allelic Composition: Mecp2^tm1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1.1Jtc/Mecp2⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm4.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm5.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm6.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm3.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0001263	weight loss	"progressive reduction of body weight below normal average for age" [J:45400]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Pplt/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N
MP:0001360	abnormal social investigation	"altered behavior of animals to approach and examine other animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tor1a^tm1Wtd/Tor1a^tm2Wtd Genetic Background: involves: 129S1/Sv Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x C57BL/6)F1 Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1 Allelic Composition: Mecp2^tm1Bird/Y,Tg(dlx5a-cre)1Mekk/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * CD-1 * FVB/N Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy Allelic Composition: Mecp2^tm1Bird/Y,Pvalb^{tm1.1(cre)Aibs}/Pvalb⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
MP:0001363	increased anxiety-related response	"when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]	Show Allelic Composition: Tor1a^tm1Wtd/Tor1a^tm2Wtd Genetic Background: involves: 129S1/Sv Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6
MP:0001364	decreased anxiety-related response	"when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]	Show Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1 Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy Allelic Composition: Mecp2^tm4.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm5.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm6.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0001392	abnormal locomotor activity	"altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^em1Dkatz/Mecp2⁺,Tyr^c-ch/Tyr^c-ch Genetic Background: FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J
MP:0001393	ataxia	"inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Mecp2⁺,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA/J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Pvalb^{tm1.1(cre)Aibs}/Pvalb⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: Mecp2^tm2.1Jae/Y Genetic Background: involves: 129/Sv * C57BL/6
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: Mapt^{tm1(Mecp2)Jae}/Mapt⁺ Genetic Background: involves: 129/Sv * C57BL/6 Allelic Composition: Mecp2^tm1Jchr/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1.1Jae/Mecp2⁺ Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Mecp2⁺,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA/J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm2.1Jae/Y Genetic Background: involves: 129/Sv * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL Allelic Composition: Mecp2^tm1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Joez/Mecp2⁺ Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm2.1Meg/Y Genetic Background: Not Specified Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * 129/SvJ Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1.1Jtc/Mecp2⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J
MP:0001405	impaired coordination	"reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: 129S7/SvEvBrd-Mecp2^tm1Hzo Allelic Composition: Mecp2^tm1Hzo/Mecp2⁺ Genetic Background: 129S7/SvEvBrd-Mecp2^tm1Hzo Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1Pplt/Mecp2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x C57BL/6)F1 Allelic Composition: Mecp2^tm1Bird/Y,Tg(dlx5a-cre)1Mekk/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * CD-1 * FVB/N Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mapt^{tm1(Setdb1)Akba}/Mapt⁺,Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N Allelic Composition: Mapt^{tm1(Setdb1)Akba}/Mapt^{tm1(Setdb1)Akba},Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL Allelic Composition: Mecp2^tm1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm2.1Meg/Y Genetic Background: Not Specified Allelic Composition: Mecp2^tm3Meg/Y Genetic Background: B6.129-Mecp2^tm3Meg Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1.1Jtc/Mecp2⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Pvalb^{tm1.1(cre)Aibs}/Pvalb⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2G273X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy Allelic Composition: Mecp2^tm1Bird/Y,Pvalb^{tm1.1(cre)Aibs}/Pvalb⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
MP:0001407	short stride length	"reduced average distance between steps" [J:34193]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001408	stereotypic behavior	"repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s wrong with my mouse?:ISBN 0-471-31639-3]	Show Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
MP:0001409	increased stereotypic behavior	"more frequent incidence of repetitive, invariant, perseverative motor patterns that do not appear to be purposeful" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, MGI:CLS, J:57125]	Show Allelic Composition: Mecp2^tm1Jchr/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: 129S7/SvEvBrd-Mecp2^tm1Hzo Allelic Composition: Mecp2^tm1Hzo/Mecp2⁺ Genetic Background: 129S7/SvEvBrd-Mecp2^tm1Hzo Allelic Composition: Mecp2^tm1Bird/Y,Tg(dlx5a-cre)1Mekk/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * CD-1 * FVB/N Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * 129/SvJ Allelic Composition: Mecp2^tm1Bird/Y,Sst^{tm2.1(cre)Zjh}/Sst⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6
MP:0001441	increased grooming behavior	"increased amount of time spent cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy
MP:0001447	abnormal nest building behavior	"deviation from the usual behavior of mice to build sleeping nests out of any available materials; also of female mice to bulid nests to protect offspring" [J:42758, What s wrong with my mouse?:ISBN 0-471-31639-3]	Show Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x C57BL/6)F1 Allelic Composition: Mecp2^tm1Bird/Y,Tg(dlx5a-cre)1Mekk/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * CD-1 * FVB/N Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N
MP:0001454	abnormal cued conditioning behavior	"defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light)" [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1
MP:0001463	abnormal spatial learning	"defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N
MP:0001469	abnormal contextual conditioning	"defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), or the environmental context in this case)" [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1
MP:0001473	reduced long term potentiation	"less than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science:ISBN 0-8385-8034-3]	Show Allelic Composition: Mecp2^tm2Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺,Tg(CAG-cre/Esr1)5Amc/? Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0001489	decreased startle reflex	"greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]	Show Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x C57BL/6)F1 Allelic Composition: Mecp2^tm1Bird/Y,Tg(dlx5a-cre)1Mekk/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * CD-1 * FVB/N Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm1Bird/Y,Pvalb^{tm1.1(cre)Aibs}/Pvalb⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
MP:0001492	piloerection	"the involuntary bristling of hairs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N
MP:0001511	disheveled coat	"coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB
MP:0001513	limb grasping	"mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺,Tg(CAG-cre/Esr1)5Amc/? Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm2Bird/Y,Tg(CAG-cre/Esr1)5Amc/0 Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum1^M1Jus/Sum1⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum2^M1Jus/Sum2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum4^M1Jus/Sum4⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum5^M1Jus/Sum5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm2.1Meg/Y Genetic Background: Not Specified Allelic Composition: Mecp2^tm3Meg/Y Genetic Background: B6.129-Mecp2^tm3Meg Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * 129/SvJ Allelic Composition: Mecp2^tm1.1Jtc/Mecp2^tm1.1Jtc Genetic Background: involves: 129S6/SvEvTac * 129/SvJ Allelic Composition: Mecp2^tm1.1Dhy/Mecp2⁺ Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy
MP:0001516	abnormal motor coordination/ balance	"altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
MP:0001552	increased circulating triglyceride level	"higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0001629	abnormal heart rate	"greater than or fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J
MP:0001636	irregular heartbeat	"uneven timing of heart contraction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:33038]	Show Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J
MP:0001661	extended life span	"persistence of life for a longer period than is the norm for an organism" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum1^M1Jus/Sum1⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum2^M1Jus/Sum2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum4^M1Jus/Sum4⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum5^M1Jus/Sum5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
MP:0001711	abnormal placenta		Show Allelic Composition: Fuom^tm1Ckp/Fuom⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Mitoh/Mecp2⁺ Genetic Background: Not Specified
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1Pplt/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001851	eye inflammation	"local accumulation of fluid, plasma proteins, and leukocytes in the eye" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y,Sum2^M1Jus/Sum2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum4^M1Jus/Sum4⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum5^M1Jus/Sum5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
MP:0001925	male infertility	"inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Kcnu1^tm1.2Clin/Kcnu1⁺ Genetic Background: B6.Cg-Kcnu1^tm1.2Clin Allelic Composition: Mecp2^tm1.1Vnar/Mecp2^tm1.1Vnar Genetic Background: B6N.129-Mecp2^tm1.1Vnar
MP:0001926	female infertility	"inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]	Show Allelic Composition: Mecp2^em1Dkatz/Mecp2⁺,Tyr^c-ch/Tyr^c-ch Genetic Background: FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J
MP:0001943	abnormal respiration	"anomaly in the movement of gases into and out of the lung " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Chat^tm2(cre)Lowl/Chat⁺,Mecp2^tm2Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
MP:0001951	abnormal breathing	"irregular or atypical breathing pattern " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489]	Show Allelic Composition: Mecp2^tm1.1Jae/Mecp2⁺ Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺,Tg(CAG-cre/Esr1)5Amc/? Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1 Allelic Composition: Mecp2^tm2Bird/Y,Tg(CAG-cre/Esr1)5Amc/0 Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * 129/SvJ Allelic Composition: Mecp2^tm1.1Jtc/Mecp2^tm1.1Jtc Genetic Background: involves: 129S6/SvEvTac * 129/SvJ
MP:0001954	respiratory distress	"physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]	Show Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N
MP:0001957	apnea	"absence of breathing; sometimes episodic" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17384]	Show Allelic Composition: Mecp2^tm1.1Jae/Mecp2⁺ Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Chat^tm2(cre)Lowl/Chat⁺,Mecp2^tm2Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
MP:0001963	abnormal hearing	"anomaly in the ability to receive auditory stimuli" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001968	abnormal touch/ nociception	"change in the ability to sense contact with objects or in the ability to sense pain, most often registered by mechanoreceptors in the skin and mucous membranes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x C57BL/6)F1 Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1
MP:0001973	increased thermal nociceptive threshold	"a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]	Show Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x C57BL/6)F1
MP:0002062	abnormal conditioning behavior	"inability to change the frequency or form of a behavior as a result of the influence of the environment " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002064	seizures	"sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tor1a^tm1Wtd/Tor1a^tm2Wtd Genetic Background: involves: 129S1/Sv Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy Allelic Composition: Mecp2^tm1Bird/Y,Sst^{tm2.1(cre)Zjh}/Sst⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6
MP:0002065	abnormal fear/anxiety-related behavior	"altered response in tests for fear or anxiety related behaviors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002066	abnormal motor capabilities/coordination/movement	"altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tor1a^tm1Wtd/Tor1a^tm2Wtd Genetic Background: involves: 129S1/Sv Allelic Composition: Mbd2^tm1Bh/Mbd2^tm1Bh,Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm4.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm5.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm6.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm3.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ins2^Akita/Ins2⁺ Genetic Background: C57BL/6-Ins2^Akita/J Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL Allelic Composition: Mbd2^tm1Bh/Mbd2^tm1Bh,Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Pplt/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Y,Tg(CAG-cre/Esr1)5Amc/0 Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mapt^{tm1(Setdb1)Akba}/Mapt⁺,Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N Allelic Composition: Mapt^{tm1(Setdb1)Akba}/Mapt^{tm1(Setdb1)Akba},Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-Setdb1)1Akba/0,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL Allelic Composition: Mecp2^tm1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Bdnf^tm3Jae/Bdnf^tm3Jae,Mecp2^tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J Allelic Composition: Bdnf^tm3Jae/Bdnf⁺,Mecp2^tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J Allelic Composition: Col1a1^{tm8(CAG-BDNF)Jae}/Col1a1⁺,Mecp2^tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2G273X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm2.1Meg/Y Genetic Background: Not Specified Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * 129/SvJ Allelic Composition: Mecp2^tm1.1Jtc/Mecp2^tm1.1Jtc Genetic Background: involves: 129S6/SvEvTac * 129/SvJ Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy Allelic Composition: Mecp2^tm4.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm5.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm6.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Pvalb^{tm1.1(cre)Aibs}/Pvalb⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl Allelic Composition: Mecp2^tm1Bird/Y,Sst^{tm2.1(cre)Zjh}/Sst⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J Allelic Composition: Mecp2^em1Dkatz/Y,Tyr^c-ch/Tyr^c-ch Genetic Background: FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J
MP:0002098	abnormal vibrissae morphology	"irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002100	abnormal tooth morphology	"atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Mecp2^tm1.1Bird Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Met^tm1Cbm/Met^tm1Cbm Genetic Background: involves: ICR Allelic Composition: Mecp2^tm3.1Bird/Mecp2^tm3.1Bird Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6
MP:0002175	low brain weight	"lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mapt^{tm1(Mecp2)Jae}/Mapt⁺ Genetic Background: involves: 129/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA/J Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Col1a1^{tm8(CAG-BDNF)Jae}/Col1a1⁺,Mecp2^tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2R270X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y,Tg(MECP2G273X/GFP)#Hzo/0 Genetic Background:* involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * FVB Allelic Composition: Mecp2^tm2.1Meg/Y Genetic Background: Not Specified Allelic Composition: Mecp2^tm3Meg/Y Genetic Background: B6.129-Mecp2^tm3Meg Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0002176	high brain weight	"greater than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm2.1Jae/Y Genetic Background: involves: 129/Sv * C57BL/6
MP:0002204	abnormal neurotransmitter physiology	"aberrant function or production of endogenous signaling molecules secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002272	abnormal nervous system electrophysiology	"anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N
MP:0002286	cryptorchism	"failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Tg(Nes-cre)1Kln/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
MP:0002327	abnormal respiratory function	"anomaly in any measure of the processes involved in respiration" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N
MP:0002574	increased vertical activity	"greater than average time spent jumping or rearing " [J:72576, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1
MP:0002690	akinesia	"absence of movement or loss of the ability to move such as temporary or prolonged paralysis or "freezing in place"" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:82238]	Show Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez
MP:0002757	reduced vertical activity	"lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Mecp2^tm1Pplt/Mecp2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002801	abnormal long-term recognition memory	"defects in long-term memory for objects that is consolidated over hours and days after training." [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1.1Jtc/Mecp2⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
MP:0002804	abnormal motor learning	"defects in the ability to repeat a motor task requiring well coordinated movements and balance; measures cerebellar dependent learning" [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm4.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm6.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002833	increased heart weight	"greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]	Show Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0002882	abnormal neuron	"anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA/J
MP:0002906	susceptibility to pharmacologically induced seizures	"inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]	Show Allelic Composition: Mecp2^tm3Meg/Y Genetic Background: B6.129-Mecp2^tm3Meg
MP:0002910	abnormal excitatory postsynaptic currents	"defect in the size or duration of currents detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock
MP:0002912	abnormal excitatory postsynaptic potential	"defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0002981	increased liver weight	"a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0003107	abnormal response to novelty	"alteration in amount of exploration/investigation of a novel object, situation or environment" [CFG:Center for Functional Genomics, Northwestern University]	Show Allelic Composition: Hey1^tm1Kkb/Hey1^tm1Kkb,Heyl^tm1Kkb/Heyl^tm1Kkb Genetic Background: B6.Cg-Hey1^tm1Kkb Heyl^tm1Kkb
MP:0003111	abnormal nucleus morphology	"abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
MP:0003212	susceptibility to age related obesity	"increased probability of excessive weight gain that is progressive with age" [RGD:Rat Genome Database submission]	Show Allelic Composition: Mecp2^tm1.1Jae/Mecp2⁺ Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Mecp2⁺,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA/J
MP:0003233	prolonged QT interval	"increase in the length of time required for ventricular depolarization and repolarization to occur, usually as a result of increased repolarization time" [J:93197, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J
MP:0003312	abnormal locomotor coordination	"reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0003313	abnormal locomotor activation	"altered ability or desire of an animal to initiate locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J
MP:0003459	increased fear-related response	"greater emotional response related to anticipation of specific pain or danger" [CFG:Center for Functional Genomics, Northwestern University]	Show Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1.1Jtc/Mecp2⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6
MP:0003461	abnormal response to novel object	"altered investigative behavior from controls in reactions associated with exposing an animal to a novel object" [CFG:Center for Functional Genomics, Northwestern University]	Show Allelic Composition: Hey1^tm1Kkb/Hey1^tm1Kkb,Heyl^tm1Kkb/Heyl^tm1Kkb Genetic Background: B6.Cg-Hey1^tm1Kkb Heyl^tm1Kkb
MP:0003633	abnormal nervous system physiology		Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock
MP:0003849	greasy coat	"fur is oily in appearance or texture" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Hzo/Y Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
MP:0003928	increased heart rate variability	"increased variation of beat-to-beat intervals of the heart, usually indicitive of a healthy heart" [RGD:Rat Genome Database submission]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J
MP:0003964	abnormal noradrenaline level	"aberrant concentration of this precursor of epinephrine that is a widespread central and autonomic neurotransmitter" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0003997	tonic-clonic seizures	"increased number or decreased threshold for the induction of a seizure characterized by initial rigidity followed by rhythmic jerking movements" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Jtc/Mecp2⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1Bird/Y,Sst^{tm2.1(cre)Zjh}/Sst⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0004085	abnormal heartbeat	"anomaly in the appearance of regularly spaced contractions of the heart" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J
MP:0004170	abnormal orbitofrontal cortex morphology	"any malformation or absence of the region of the cerebral cortex covering the basal surface of the frontal lobes; this region normally controls emotion and decision making" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1Vnar/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl Allelic Composition: Mecp2^tm1.1Vnar/Mecp2^tm1.1Vnar Genetic Background: B6N.129-Mecp2^tm1.1Vnar
MP:0004183	abnormal sympathetic nervous system physiology	"anomaly in the function of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and mediates the body s response to stressful situations" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J
MP:0004485	increased response of heart to induced stress	"increase in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J
MP:0004753	abnormal miniature excitatory postsynaptic currents	"defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock
MP:0004792	abnormal synaptic vesicle number	"anomaly in the number of the small, membrane bound sacs that contain various neurotransmitter molecules that are concentrated at pre-synaptic membranes and release the neurotransmitters by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock
MP:0004924	abnormal behavior	"anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1Hzo/Mecp2⁺ Genetic Background: 129S7/SvEvBrd-Mecp2^tm1Hzo Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2Bird/Mecp2⁺,Tg(CAG-cre/Esr1)5Amc/? Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm2Bird/Y,Tg(CAG-cre/Esr1)5Amc/0 Genetic Background:* involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Joez/Mecp2⁺ Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm4.1Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm5.1Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm2.1Meg/Y Genetic Background: Not Specified Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy Allelic Composition: Mecp2^tm1.1Dhy/Mecp2⁺ Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy Allelic Composition: Mecp2^tm4.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm5.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm6.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm6.1Bird/Mecp2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004994	abnormal brain wave pattern	"any anomaly in the standard pattern of rhythmic and rapid fluctuation of electrical potential between parts of the brain, often visualized on an electroencephalogram (EEG); the pattern is often measured to diagnose neurological conditions such as seizure disorders (epilepsy)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez
MP:0004998	decreased CNS synapse formation	"a reduction in the frequency of the process of generating the initial connections between an axon and effector tissue or neuron" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock
MP:0005150	cachexia	"general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N
MP:0005178	increased total circulating cholesterol level	"greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0005202	lethargy	"mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1Pplt/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1Pplt/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Bdnf^tm3Jae/Bdnf^tm3Jae,Mecp2^tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S/Sv * C57BL/6 Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum1^M1Jus/Sum1⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum2^M1Jus/Sum2⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum4^M1Jus/Sum4⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y,Sum5^M1Jus/Sum5⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6
MP:0005333	decreased heart rate	"fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J
MP:0005402	abnormal action potential	"change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6 Allelic Composition: Bdnf^tm3Jae/Bdnf^tm3Jae,Mecp2^tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J Allelic Composition: Col1a1^{tm8(CAG-BDNF)Jae}/Col1a1⁺,Mecp2^tm1.1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA/J
MP:0005426	tachypnea	"rapid breathing" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1.1Jae/Mecp2⁺ Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6
MP:0005534	decreased body temperature	"less than the level of heat natural to a living being" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J
MP:0005535	abnormal body temperature	"deviation in the level of heat natural to a living being" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6
MP:0005573	increased breathing frequency	"greater than the normal number of breaths in a given period of time" [RGD:Rat Genome Database submission]	Show Allelic Composition: Mecp2^tm1.1Bird/Y,Sqle^Sum3-Jus/Sqle⁺ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Mecp2^tm1.1Irsf/Mecp2⁺ Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0005586	decreased tidal volume	"less than the normal volume of air inspired or expired during each normal respiratory cycle" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N
MP:0006277	abnormal parasympathetic nervous system physiology	"anomaly in the function of the craniosacral portion of the autonomic nervous system" [Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:78031]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J
MP:0008143	abnormal dendrite morphology	"any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1Vnar/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl Allelic Composition: Mecp2^tm1.1Vnar/Mecp2^tm1.1Vnar Genetic Background: B6N.129-Mecp2^tm1.1Vnar Allelic Composition: Mecp2^tm1.1Meg/Y Genetic Background: B6.129-Mecp2^tm1.1Meg
MP:0008265	abnormal hippocampus CA2 region morphology		Show Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 Allelic Composition: Mecp2^tm1Jae/Y,Tg(Nes-cre)1Atp/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N Allelic Composition: Mecp2^tm1Jae/Y,Tg(Camk2a-cre)93Kln/0 Genetic Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA/J Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0008489	postnatal slow weight gain	"the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * 129/SvJ
MP:0008908	increased total fat pad weight	"greater than average weight of the fat pads" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
MP:0008948	decreased neuron number	"fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock
MP:0008950	ventricular tachycardia	"paroxysmal rapid beating of the heart originating in an ectopic focus in the heart ventricle" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J
MP:0009141	increased prepulse inhibition	"increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1Bird/Y,Tg(dlx5a-cre)1Mekk/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * CD-1 * FVB/N Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N
MP:0009142	decreased prepulse inhibition	"decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x C57BL/6)F1 Allelic Composition: Mecp2^tm1Bird/Y Genetic Background: (129S6.129P2-Mecp2^tm1Bird x FVB/N)F1
MP:0009355	increased liver triglyceride level	"higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: B6.Cg-Mecp2^tm1.1Jae
MP:0009435	abnormal miniature inhibitory postsynaptic currents	"defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an inhibitory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N Allelic Composition: Mecp2^tm1.1Meg/Y Genetic Background: B6.129-Mecp2^tm1.1Meg
MP:0009454	impaired contextual conditioning	"decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and the neutral, unchanging environment (the conditioned stimulus (CS), or the environmental context in this case)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1.1Irsf/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
MP:0009456	impaired cued conditioning behavior	"decrease in the ability of an animal to learn and remember an association between an aversive experience (the unconditioned stimulus (US), usually a shock) and a neutral stimulus (the conditioned stimulus (CS), usually an auditory cue or light flash)" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez Allelic Composition: Mecp2^tm1Bird/Y,Pvalb^{tm1.1(cre)Aibs}/Pvalb⁺ Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl
MP:0009658	increased placenta apoptosis	"increase in the number of cells of the placenta undergoing programmed cell death" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fuom^tm1Ckp/Fuom⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Mitoh/Mecp2⁺ Genetic Background: Not Specified
MP:0009732	ventricular premature beat	"a heartbeat is initiated by abnormal electrical activation originating in the heart ventricles rather than by the sinoatrial node, the normal heartbeat initiator, before a normal heartbeat would occur" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J Allelic Composition: Mecp2^tm1Jae/Y,Chat^tm2(cre)Lowl/Chat⁺ Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J
MP:0009939	abnormal hippocampus neuron morphology		Show Allelic Composition: Mecp2^tm1.1Dhy/Y Genetic Background: C57BL/6N-Mecp2^tm1.1Dhy
MP:0009940	abnormal hippocampus pyramidal cell morphology	"any structural anomaly of the projection neuron in the pyramidal layer of the hippocampus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Joez/Y Genetic Background: B6.129-Mecp2^tm1.1Joez
MP:0010053	decreased grip strength	"reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]	Show Allelic Composition: Mecp2^tm1Bird/Y,Tg(Slc32a1-cre)2.1Hzo/0 Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * FVB/N Allelic Composition: Mecp2^tm1.1Jtc/Y Genetic Background: involves: 129S6/SvEvTac * C57BL/6
MP:0010070	decreased serotonin concentration	"reduction in the amount per unit of biochemical messenger and regulator, found in the CNS, gastrointestinal tract, and produced by platelets that mediates neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010162	increased brain cholesterol level	"greater than normal amount in the brain of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Mecp2^tm1.1Jae/Y Genetic Background: B6.Cg-Mecp2^tm1.1Jae
MP:0010382	abnormal dosage compensation, by inactivation of X chromosome	"anomaly in the process of compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex" [GO:0009048]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock
MP:0010519	atrioventricular block	"a partial or complete obstruction of the impulse that originates in the atria or sinoatrial node from reaching or transmitting through the atrioventricular node to the ventricles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Mecp2^tm1.1Bird/Y Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm1.1Bird/Mecp2⁺ Genetic Background: B6.129P2(C)-Mecp2^tm1.1Bird/J Allelic Composition: Mecp2^tm2Bird/Y Genetic Background: B6.129P2-Mecp2^tm2Bird/J
MP:0011110	partial preweaning lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Fuom^tm1Ckp/Fuom⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Mecp2^tm1.1Mitoh/Mecp2⁺ Genetic Background: Not Specified Allelic Composition: Mecp2^tm1.1Mitoh/Mecp2^tm1.1Mitoh Genetic Background: Not Specified
MP:0012006	abnormal hippocampus physiology	"any functional anomaly related to processes in the deep lying structure of the cerebrum involved with memory storage and spatial navigation" [MPD:Molly]	Show Allelic Composition: Dstn^corn1/Dstn^corn1,Cxcr2^tm1Mwm/Cxcr2^tm1Mwm Genetic Background: involves: 129S2/SvPas * A/WySn * BALB/c * brachy stock

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