ENSMUSG00000031422


Mus musculus

Features
Gene ID: ENSMUSG00000031422
  
Biological name :Morf4l2
  
Synonyms : Morf4l2 / Mortality factor 4-like protein 2 / Q9R0Q4
  
Possible biological names infered from orthology : mortality factor 4 like 2 / Q15014
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F1
Gene start: 136732942
Gene end: 136743690
  
Corresponding Affymetrix probe sets: 10606876 (MoGene1.0st)   1415778_at (Mouse Genome 430 2.0 Array)   1439413_x_at (Mouse Genome 430 2.0 Array)   1439432_x_at (Mouse Genome 430 2.0 Array)   1456743_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119517
Ensembl peptide - ENSMUSP00000132643
Ensembl peptide - ENSMUSP00000131909
Ensembl peptide - ENSMUSP00000129774
Ensembl peptide - ENSMUSP00000126363
Ensembl peptide - ENSMUSP00000121632
Ensembl peptide - ENSMUSP00000121412
Ensembl peptide - ENSMUSP00000120404
Ensembl peptide - ENSMUSP00000033797
Ensembl peptide - ENSMUSP00000108718
Ensembl peptide - ENSMUSP00000108720
Ensembl peptide - ENSMUSP00000108722
Ensembl peptide - ENSMUSP00000115303
Ensembl peptide - ENSMUSP00000115911
NCBI entrez gene - 56397     See in Manteia.
MGI - MGI:1927167
RefSeq - XM_006528584
RefSeq - NM_001168225
RefSeq - NM_001168226
RefSeq - NM_001168227
RefSeq - NM_001168228
RefSeq - NM_001168229
RefSeq - NM_001168230
RefSeq - NM_019768
RefSeq Peptide - NP_001161699
RefSeq Peptide - NP_001161701
RefSeq Peptide - NP_001161702
RefSeq Peptide - NP_062742
RefSeq Peptide - NP_001161697
RefSeq Peptide - NP_001161698
RefSeq Peptide - NP_001161700
swissprot - A2AEB8
swissprot - A2AEB7
swissprot - A2AEB6
swissprot - A2AEB5
swissprot - A2AEB4
swissprot - Q9R0Q4
swissprot - A2AEB9
swissprot - A2AEB3
Ensembl - ENSMUSG00000031422
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 morf4l1ENSDARG00000041155Danio rerio
 MORF4L1ENSGALG00000008146Gallus gallus
 Q15014ENSG00000123562Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P60762 / Morf4l1 / Mus musculus mortality factor 4 like 1 (Morf4l1), transcript variant 3, mRNA. / Q9UBU8* / mortality factor 4 like 1*ENSMUSG0000006227069


Protein motifs (from Interpro)
Interpro ID Name
 IPR008676  MRG
 IPR026541  MRG domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IBA
 biological_processGO:0006342 chromatin silencing IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0016575 histone deacetylation IBA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0043967 histone H4 acetylation IBA
 biological_processGO:0043968 histone H2A acetylation IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051155 positive regulation of striated muscle cell differentiation IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Morf4l2tm1.1Kto/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Morf4l1tm1Kto/Morf4l1tm1Kto,Morf4l2tm1.1Kto/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rb1tm1Tyj/Rb1tm1Tyj
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Morf4l2tm1.1Kto/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Morf4l2tm1.1Kto/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Morf4l1tm1Kto/Morf4l1tm1Kto,Morf4l2tm1.1Kto/Y
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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