ENSMUSG00000031697


Mus musculus

Features
Gene ID: ENSMUSG00000031697
  
Biological name :Orc6
  
Synonyms : Orc6 / origin recognition complex subunit 6
  
Possible biological names infered from orthology : Q9Y5N6
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C3
Gene start: 85299632
Gene end: 85308278
  
Corresponding Affymetrix probe sets: 10573615 (MoGene1.0st)   1417037_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126925
Ensembl peptide - ENSMUSP00000147901
Ensembl peptide - ENSMUSP00000147488
Ensembl peptide - ENSMUSP00000147381
Ensembl peptide - ENSMUSP00000034132
NCBI entrez gene - 56452     See in Manteia.
MGI - MGI:1929285
RefSeq - NM_019716
RefSeq - NM_001163791
RefSeq Peptide - NP_001157263
RefSeq Peptide - NP_062690
swissprot - Q66JV6
swissprot - A0A1B0GRE5
swissprot - A0A1B0GR56
swissprot - Q3TQX1
swissprot - A0A1B0GSE2
Ensembl - ENSMUSG00000031697
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 orc6ENSDARG00000075682Danio rerio
 ORC6ENSGALG00000004342Gallus gallus
 ORC6ENSG00000091651Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008721  Origin recognition complex, subunit 6
 IPR020529  Origin recognition complex, subunit 6, metazoa/plant
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0051782 negative regulation of cell division IEA
 cellular_componentGO:0000808 origin recognition complex IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Nxntm1a(EUCOMM)Wtsi/Nxntm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nxntm1a(EUCOMM)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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